ReDuNing injection, prepared from a combination of Gardenia Jasminoides fruits, Lonicera japonica flower buds, and the Artemisia annua aerial part, is extensively used for treatment of viral upper respiratory tract infections in China. Iridoids, organic acids, and flavonoids are likely important compounds of the herbal injection because of their reported pharmacological properties. This study w...

Three new minor iridoids were isolated from the roots of Scrophularia ningpoensis. They were elucidated as 8-Oferuloylharpagide, 8-O-(2-hydroxy-cinnamoyl)harpagide and 6-O-a-D-galactopyranosylharpagoside. # 1998 Published by Elsevier Science Ltd. All rights reserved.

A previous study showed that the contents of caffeoylquinic acids and iridoids, the major bioactive components in the postharvest Lonicera japonica Thunb., were induced by enhanced ultraviolet (UV)-A or UV-B irradiation. To clarify the UV-responsive key enzymes in the bioactive metabolites biosynthetic pathway and the related plant defense mechanism in L. japonica, 2DE in combination with MALDI...

Members of the family Bignoniaceae are mostly found in tropical and neo-tropical regions in America, Asia and Africa, although some of them are cultivated in other regions as ornamentals. Species belonging to this family have been extensively studied in regard to their pharmacological properties (as extracts and isolated compounds). The aim of this review is to summarize the reported scientific...

Cultivated blueberry (Vaccinium corymbosum, Vaccinium angustifolium, Vaccinium darrowii, and Vaccinium virgatum) is an economically important fruit crop native to North America and a member of the Ericaceae family. Several species in the Ericaceae family including cranberry, lignonberry, bilberry, and neotropical blueberry species have been shown to produce iridoids, a class of pharmacologicall...

Iridoid profiles of honeysuckle berry were studied. Compounds were identified by ultra-performance liquid chromatography coupled with electrospray ionization mass spectrometry UPLC-ESI-qTOF-MS/MS in positive and negative ions mode. The MS fragmentation pathways of detected iridoid glycosides were also studied in both modes. In the negative ESI mass spectra, iridoids with a methyl ester or lacto...

In this paper we show the seasonal and diurnal variation in the content of the four iridoids found in cultivars of Antirrhinum majus, antirrhinoside, antirrhide, 5-glucosyl-antirrhinoside and linarioside. The seasonal variation in total iridoid content showed a marked bimodal distribution with high total values (around 100mg/g dry matter) early and late in the season and a very low content of a...

Chronic inflammation is associated with various chronic illnesses including immunity disorders, cancer, neurodegeneration, and vascular diseases. Iridoids are compounds with anti-inflammatory properties. However their anti-inflammatory mechanism remains unclear. Here, we report that scropolioside B, isolated from a Tibetan medicine (Scrophularia dentata Royle ex Benth.), blocked expressions of ...

Three new iridoids, Gardenal-I (1), Gardenal-II (2) and Gardenal-III (3), together with nine known iridoid glycosides; geniposide (4), 6-β-hydroxy geniposide (5), 6-α-hydroxy geniposide (6), 6-α-methoxy geniposide (7), feretoside (8), genipin-1-β-gentiobioside (9), shanzhiside (10), lamalbidic acid (11) and picrocrocinic acid (12) were isolated from EtOH extract of G. gasminoides. The structure...