The NASA/IPAC Extragalactic Database (NED) is an impressive tool for finding near-exhaustive information on millions of astrophysical objects. Here, we outline a small systematic error that occurs in NED because low-redshift approximation used when making the correction from redshifts heliocentric frame to cosmic microwave background (CMB) rest frame. It means historically systematically misrep...

December 22, 2016 Type Package Title Identification of mutational clusters in protein quaternary structures. Version 1.6.0 Date 2014-09-25 Author Gregory Ryslik, Yuwei Cheng, Hongyu Zhao Maintainer Gregory Ryslik Description Identifies clustering of somatic mutations in proteins over the entire quaternary structure. License GPL-2 biocViews Clustering, Proteomics, Somat...

February 1, 2017 Type Package Title Identification of mutational clusters in protein quaternary structures. Version 1.6.0 Date 2014-09-25 Author Gregory Ryslik, Yuwei Cheng, Hongyu Zhao Maintainer Gregory Ryslik Description Identifies clustering of somatic mutations in proteins over the entire quaternary structure. License GPL-2 biocViews Clustering, Proteomics, Somati...

There are major gaps in the measurement of adoption and stringency countries’ climate actions policies, notably a manner coherent across countries, time, sectors instrument types. The policies framework (CAPMF) aims to fill this gap. It is structured harmonised mitigation policy database that informs about action. CAPMF was developed under International Programme for Action on Climate (IPAC). c...

The native Invaplex (InvaplexNAT) vaccine and adjuvant is an ion exchange-purified product derived from the water extract of virulent Shigella species. The key component of InvaplexNAT is a high-molecular-mass complex (HMMC) consisting of the Shigella lipopolysaccharide (LPS) and the invasin proteins IpaB and IpaC. To improve product purity and immunogenicity, artificial Invaplex (InvaplexAR) w...

November 21, 2016 Type Package Title Identification of mutational clusters in protein quaternary structures. Version 1.6.0 Date 2014-09-25 Author Gregory Ryslik, Yuwei Cheng, Hongyu Zhao Maintainer Gregory Ryslik Description Identifies clustering of somatic mutations in proteins over the entire quaternary structure. License GPL-2 biocViews Clustering, Proteomics, Somat...

Pull-down assays can identify members of protein complexes but suffer from co-isolation of contaminants. The problem is particularly acute when the specifically interacting partners are of low-abundance and/or bind transiently with low affinity. To differentiate true interacting partners from contaminants, we have combined SILAC labelling with a proteomic method called "Interactomes by Parallel...

Shigella flexneri, the causative agent of shigellosis, is a gram-negative bacterial pathogen that initiates infection by invading cells within the colonic epithelium. Contact with host cell surfaces induces a rapid burst of protein secretion via the Shigella type III secretion system (TTSS). The first proteins secreted are IpaD, IpaB, and IpaC, with IpaB and IpaC being inserted into the host ce...

The second author was invited to write this paper by the Intellectual Property Advisory Committee (IPAC) of the UK Patent Office. She is grateful to the Director of the Intellectual Property Institute, Paul Leonard, who provided a small grant to employ Padraig Dixon, who drafted much of the eventual text. We also acknowledge the assistance of Dr. Mark Rogers, Harris Manchester College, in respe...

The NASA/IPAC Extragalactic I~atabase (INED) is an electronic research tool which provides uniquely powerful access to published multi-wavelength data on extragalactic objects. It consists of a computer database with a broad range of published information, and a user interface which allows fast and flexiblc~ retrieval of the information via the lntm-net. It is accessible anonymously and free of...