We present a systematic investigation of the effect of solvent hydrophobicity (alkyl chain length) on the gelation kinetics and the phase states of the polypeptide gelatin in imidazolium based ionic liquid (IL) solutions. We have observed that IL concentration and hydrophobicity had dramatic influences on the thermal and viscoelastic properties of gelatin ionogels. Gelation concentration cg was...

In recent years, chitosan nanoparticles have been studied widely for protein delivery. In this study, Hemiscorpius lepturus (HL) venom was encapsulated in chitosan nanoparticles. The aim of the present work was to carry out a systematic study for preparing biocompatible and biodegradable nanoparticles for loading HL scorpion venom and to evaluate their potential as an antigen delivery system. I...

Herein we report on the self-assembly of a family of Fmoc-depsipeptides into nanofibers and hydrogels. We show that fiber formation occurs in depsipeptide structures in which the fluorenyl group is closely associated and that side-chain charge and sequence affect the extent of self-assembly and subsequent gelation. Using fluorescence emission spectroscopy and circular dichroism, we show that se...

The effects of a cationic surfactant, cetyltrimethylammonium bromide (CTAB), on the gelation of methylcellulose (MC) in aqueous solutions have been investigated by micro differential scanning calorimetry (micro DSC) and rheology. Methylcellulose had a weight average molecular weight of 310,000 and a degree of substitution of 1.8. The concentration of MC was kept at 0.5 wt % (0.016 mM) and 1 wt ...

Structural characterization of a hydrogel consisting of an oligomeric electrolyte, poly[pyridinium-1,4-diyliminocarbonyl-1,4-phenylenemethylene chloride] (1-Cl) as an ionic gelator was carried out by static and dynamic light scattering (SLS/DLS) and small-angle neutron scattering (SANS) techniques. All the measurements were performed by changing the concentration and temperature. We have succes...

      Biodegradable nanoparticulate carriers, have important potential applications for administration of therapeutic molecules. Chitosan based nanoparticles have attracted a lot of attention upon their biological properties such as biodegradability, biocom-patibility and bioadhesivity. The aim of the present investigation was to describe the synthesis and characterization of novel biodegradabl...

Abstract: Background: Natural biopolymers or hydrogels that are biodegradable and safe from biological point of view along with their capability to retain active principle within network thus prolonging the release. The present work was undertaken explore potential mucilage mature seeds Chia (Salvia hispanica) sustain release water-soluble drugs. Losartan potassium used as a model prepare gelis...