Purpose: The study aimed to examine whether prophylactic surfactant replacement therapy (SRT) with less invasive administration (LISA) by tracheal catheterization in a group of spontaneously breathing preterm infants would improve clinical outcomes compared SRT the INtubation-SURfactantExtubation (INSURE) method.Methods: We 20 infants, 25 29 weeks gestation or birth weight than 1,250 g, treated...

There is a growing body of evidence over the last years suggesting continuous positive airway pressure (CPAP) ventilation being the first choice of ventilatory support in newborns with extremely low gestational age, and early rescue surfactant treatment being as effective as prophylactic therapy. The Intubation Surfactant Extubation procedure is discussed as an alternative procedure that may ha...

BACKGROUND Over the past years, research on neonatal resuscitation has focused on single interventions. The present study was performed to analyze the process quality of delivery room management of preterm infants born by c-section in our institution. METHODS We performed a cross-sectional study of videos of preterm infants born by c-section. Videos were analyzed according to time point, dura...

OBJECTIVE This study reports our institutional experience on the outcome after prophylactic and early rescue endotracheal instillation of surfactant within 20 minutes of birth, followed by extubation and nasal continuous positive airway pressure (NCPAP) in preterm infants <32 weeks gestational age. PATIENTS AND METHODS A total of 142 infants were prospectively studied (42, gestational age fro...

Introduction Respiratory distress syndrome (RDS) is a current cause of morbidity in premature infants resulted from surfactant deficiency. The primary aim of this randomized study was to describe the feasibility of early administration of surfactant via a thin catheter during spontaneous breathing (TEC) and compare its outcomes with the InSurE (Intubate, Surfactant, Extubate) procedure Material...

EBNEO commentaries on manuscripts relevant to evidence-based neonatal practice are welcomed and published after a formal peer-review process. To learn more visit contact Dr. Amy Keir < [email protected] > or Clyde J. Wright with questions. Surfactant deficiency is major cause of CPAP failure in extremely preterm infants. avoid harmful effects associated ...

emergence from general anesthesia can be associated with coughing, agitation, and hemodynamic disturbances. remifentanil may attenuate these responses. we have examined the effect of remifentanil on the hemodynamic response to the emergence from anesthesia and tracheal extubation. in a double-blind, randomized trial, we enrolled 50 adult patients undergoing abdominal surgery. all patients recei...

introduction respiratory distress syndrome (rds) is a current cause of morbidity in premature infants resulted from surfactant deficiency. the primary aim of this randomized study was to describe the feasibility of early administration of surfactant via a thin catheter during spontaneous breathing (tec) and compare its outcomes with the insure (intubate, surfactant, extubate) procedure material...