Intravenous immunoglobulin (IVIg) treatment was introduced as replacement therapy for patients with antibody deficiencies, but evidence suggests that a wide range of immune-mediated conditions could benefit from IVIg. The immunoglobulins are precipitated from human plasma by fractionation methods. In conclusion, the differences in basic fractionation methods and the addition of various modifica...

The systemic lupus erythematosus (SLE) is an autoimmune disorder with a broad array of clinical signs. In this research, we aimed to use intravenous immunoglobulins (IVIG) called intacglobin as monotherapy to manage an SLE in three patients. Laboratory investigations for SLE diagnosis were done, including the detection of anti-nuclear antibodies (ANA) and SLE confirmation by detecting high tite...

Intravenous Immunoglobulins (IvIg) are often administered to critically ill patients more as an act of faith than on the basis of relevant clinical studies. This particularly applies to the treatment of sepsis in adult patients, in whom the current guidelines even recommend against their use, despite that many studies demonstrated either their beneficial effects in different subsets of patients...

BACKGROUND Patients with common variable immunodeficiency often suffer from recurrent bacterial infections. Administration of immunoglobulins is a well-established treatment to reduce the frequency and severity of these infections. However, in patients with anti-IgA antibodies or side effects to previous immunoglobulin substitution therapy, administration of immunoglobulins may lead to anaphyla...

9.5 Range of Application, Dosage 9.5.1 Indications for Subcutaneous or Intramuscular Injection of Normal Immunoglobulins 9.5.2 Indications for Intravenous Injection of Normal Immunoglobulins 9.5.2.1 Primary Immunodeficiency Diseases 9.5.2.2 Secondary Immunodeficiency Diseases 9.5.2.3 High-Dose ivIg Treatment in Certain Autoimmune Diseases and Diseases of Unknown Etiology 9.5.3 Licensed Indicati...

9.5 Range of Application, Dosage 9.5.1 Indications for Subcutaneous or Intramuscular Injection of Normal Immunoglobulins 9.5.2 Indications for Intravenous Injection of Normal Immunoglobulins 9.5.2.1 Primary Immunodeficiency Diseases 9.5.2.2 Secondary Immunodeficiency Diseases 9.5.2.3 High-Dose ivIg Treatment in Certain Autoimmune Diseases and Diseases of Unknown Etiology 9.5.3 Licensed Indicati...

BACKGROUND
 This hemolytic disease of fetus and newborn is a condition in which there immunologic hemolysis fetal / neonatal red blood cells.
 OBJECTIVE: 
 To compare the efficacy intravenous immunoglobulins reducing need for exchange transfusion Rh incompatible neonates.
 MATERIALS AND METHOD: Randomized Controlled Trial was conducted from 1st September 2021 to 31st August ...