BACKGROUND There is some uncertainty whether prior use of antiplatelet (AP) drugs increases the risk of symptomatic intracerebral hemorrhage (SICH) and influences functional outcome in patients with ischemic stroke treated with intravenous thrombolysis. OBJECTIVE To assess whether prior use of AP drugs is related to outcome following intravenous tissue plasminogen activator therapy in patient...

Introduction: Intravenous general anesthetic agents are among the most important and widely used anesthetic drugs in the clinical practice. Many pharmacological studies have shown that potentiation of GABA and glycine on their receptors is the most plausible mechanism. Nevertheless, there is limited information on the effects of co-administration of two or more of these agents. However, expe...

background: icu patients especially those under mechanical ventilation or with a history of coagulation disorders are at the risk of stress ulcer development and related gi bleeding. typically h2 blockers administration showed prophylactic role to control gastric acidity. preliminary studies have shown that administration of intravenous omeperazol is effective. the object of this study was to c...

Part I of this series describes the mechanisms and types of rejection and the intravenous immunosuppressive drugs commonly used for induction or antirejection therapy. In this article, we review the commonly used oral immunosuppressive drugs. Intravenous corticosteroid methylprednisolone is included in the discussion of corticosteroids. Table 1 gives trade names, pharmacology, necessary adjustm...

Narcotic substances have a pronounced toxic effect on the entire body and can lead to disability. Despite ongoing efforts combat drug addiction, in today's society, many drugs are available for potential use. Their destructive action leads numerous adverse ocular systemic manifestations. The most frequently, drug-users people of working age, whom visual impairment restrictions labor social acti...