a bioequivalence study of two verapamil formulations (generic verapamil tablets and isoptin® tablets) was performed by comparing pharmacokinetic parameters of the parent drug and its major metabolite, norverapamil following a single dose administration of 80 mg verapamil hydrochloride in 22 healthy volunteers according to a randomized, two-period, crossover-design study. moreover, the feasibili...

there is a general consensus that climate change has impact on the intensity and frequency of rainfall events. however, very little research is available about the changes in short term rainfall extremes. the focus of this paper has been on the change in annual and monthly rainfall extremes in ontario. the results indicate a greater variability (increase and decrease) among stations for shorter...

retrotransposons (rtns) constitute informative molecular markers for plant species because of their ability to integrate into a multitude of loci throughout the genome and thereby generate insertional polymorphisms between individuals. in the present study, rtn-based molecular markers, irap (inter-retrotransposon amplified polymorphism) and remap (retrotransposon-microsatellite amplified polymo...

designing breeding programs for winter rapeseed (brassica napus l.) cultivars with improved seed and oil yields requires information about the genetic variability of traits. in this study, 28 winter rapeseed cultivars were evaluated for genetic variation and relationships between 11 agro-morphological characters during 2010 and 2011. cultivars and cultivar × year interaction showed significant ...

Three Apium graveolens (L.) varieties and cultivars within varieties were evaluated for host plant suitability to two polyphagous lepidopteran herbivores: the beet armyworm, Spodoptera exigua (Hiibner), and the cabbage looper, Trichoplusia ni (Hiibner). Overall, there were no significant differences in survivorship, developmental time, and pupal weight of S. exigua or T. ni reared on the two va...

abstract guilan is a famous province in growing rice in iran. recently, due to shortage of water, farmers' desire to use groundwater in order to grow rice in northern part of iran has been increasing rapidly. the fact that rice is sensitive to water quality, caused concern about rice cultivation sustainability in the area, especially in drought years. this study was done to investigate the spat...

this study investigates the atmospheric circulation associated with extreme rainfall events over the coastal west africa. the rainfall data of this study were obtained from the global precipitation climatology centre (gpcc), spanning from 1981 to 2010. the atmospheric datasets were also obtained from the era-interim reanalysis. the study employed the z-index to categorize dry and wet years into...

Summer maize (Zea mays L.) is one of the dominant crops in the North China Plain (NCP). Its growth is greatly influenced by the spatial-temporal variation of climatic variables, especially solar radiation, temperature and rainfall. The WOFOST (version 7.1) model was applied to evaluate the impact of climatic variability on summer maize yields using historical meteorological data from 1961 to 20...