dorzolamide ophthalmic drop is one of the most common glaucoma medications but it has a short residence time in the eye. the aim of this study is to develop ocular dorzolamide hcl nanoliposomes (drz – nanoliposomes) and to evaluate their potential use for the treatment of ocular hypertension. nanoliposomes were prepared using reverse-phase evaporation vesicle (rev) and thin layer hydration (tlh...

purpose: to evaluate the effect of intravitreal bevacizumab (ivb) injection on sustained intraocular pressure (iop) methods: this non-randomized prospective study was conducted on 359 eyes of 359 patients in amir almomenin (rasht) and labbafinejad (tehran) hospitals. after history taking and complete ocular examination, iop was measured one week and one day before injection (twice at each sessi...

purpose : to investigate intraocular pressure (iop) changes due to different serum level heights by using tonopen in acquired globes from the iran eye bank (ieb). methods : in this interventional prospective case series, serum were infused into 18 normal globes acquired from ieb by using 21g needle inserted in vitreal space through optic nerve head to change the iop by different fluid level hei...

PURPOSE To test the hypothesis that a 24-hour recording of intraocular pressure (IOP)-related measurements derived from a contact lens sensor (CLS) correlates to the rate of visual field progression in treated glaucomatous eyes. DESIGN Prospective, cross-sectional study. PARTICIPANTS Forty treated glaucomatous patients with 8 or more 24-2 visual field tests. METHODS Twenty-four-hour recor...

Purpose: To describe the methods of performing water drinking test (WDT) and its applications in glaucoma management.
 Methods: This review is based on pertinent publications retrieved by a selective search PubMed, supplemented further articles chosen authors.
 Results: Intraocular pressure (IOP) changes throughout day. IOP peak has been identified as risk factor onset progression. WD...

Achievement of target intraocular pressure is the goal of every efficient antiglaucoma therapy. Target intraocular pressure is the level of intraocular pressure which is associated with minimal likelihood of visual field or optic nerve lesion, or an existing lesion progression due to elevated intraocular pressure. Results of large clinical studies which have offered some new concepts on target ...

purpose : to evaluate intraocular pressure (iop) and anterior chamber depth (acd) change after phacoemulsification with posterior chamber intraocular lens implantation methods : in this quasi-experimental study, 84 patients with senile cataract were included. all patients had normal iop. patients with traumatic and complicated cataract, any history of uveitis, glaucoma, or other ocular disease ...

PURPOSE To distinguish 24-hour (circadian) and postural effects on intraocular pressure (IOP) in healthy young adults. METHODS Thirty-three volunteers were housed in a sleep laboratory for 1 day under a strictly controlled 16-hour light and 8-hour dark environment. Sleep was encouraged in the dark period. Intraocular pressure was measured in each eye every 2 hours using a pneumatonometer. Res...

background: ramadan fasting may alter a variety of physiological parameters which by themselves influence ocular system. here, we review the effects of ramadan fasting on the health and function of the eye. materials and methods: literature records in  pubmed/medline, web of science, embase, google scholar, and iran medex databases as well as proceedings of related meetings  from january 1986 t...