OBJECTIVE To compare anxiolysis produced by intranasal clonidine with intranasal midazolam as premedication in children undergoing surgery. DESIGN Double-blind randomized controlled study. SETTING Tertiary-care hospital, July 2009 to June 2010. PATIENTS 60 American Society of Anesthesiologists physical status I-II surgical patients aged 1-10 yr. INTERVENTION Participants randomly alloca...

imaging of the kidneys and urinary tract has a significant and critical role for diagnosis of genitourinary system diseases. although technological progress goes toward less invasive approaches, some of the current methods are still invasive and annoying. voiding cystourethrography (vcug) is the best and most accurate method for diagnosis and grading of vesicoureteral refl ux. vcug is a distres...

OBJECTIVE Acute seizure attack is a stressful experience both for health care personnel and parents. These attacks might cause morbidity and mortality among patients, so reliable methods to control the seizure preferably at home should be developed. This study was performed to measure the time needed to control seizure attacks using intranasal midazolam compared to the common treatment (intrave...

Down syndrome (DS) is a congenital autosomal disorder characterized by generalized growth and mental deficiency. Patients with down may be anxious uncooperative during dental treatment thus oral health professionals need to use physical restraints, which causes further emotional trauma. Intranasal sedation non-invasive, safe well tolerated method children. This paper presents case report of 12-...

PURPOSE The purpose of this study was to compare the safety, efficacy and recovery time of intranasal midazolam spray administered using an atomizer to orally administered chloral hydrate and promethazine for the sedation of pediatric dental patients. METHODS A randomized double-blind crossover study design was utilized in which 31 patients (mean age 41.8 months, range 26-58 months) underwent...

Intranasal administration of midazolam has been of particular interest because of the rapid and reliable onset of action, predictable effects, and avoidance of injections. The available intravenous formulation (Dormicum i.v. solution from Hoffmann-La Roche) is however less than optimal for intranasal administration due to low midazolam concentration and acidity of the formulation (pH 3.0-3.3). ...

Many drugs have been tried for premedication in children[1] amongst which midazolam and dexmedetomidine are commonly used reportedly safe effective usage during both separation as well induction of anaesthesia. Hence, we planned to carry out a study versus children via intranasal Mucosal Atomization Device. To compare the efficacy 2 6 years age This randomized was done at Dhiraj hospital, Pipar...