a 3-year-old boy was admitted to the emergency department with right lower limb pain, edema, and livedoid discoloration that occurred immediately after intramuscular injection of benzathine penicillin. the patient was diagnosed with nicolau syndrome, a rare complication of intramuscular injection presumed to be related to the inadvertent intravascular injection. it was first reported following ...

A 3-year-old boy was admitted to the emergency department with right lower limb pain, edema, and livedoid discoloration that occurred immediately after intramuscular injection of benzathine penicillin. The patient was diagnosed with Nicolau syndrome, a rare complication of intramuscular injection presumed to be related to the inadvertent intravascular injection. It was first reported following ...

INTRODUCTION Although the third stage of labour is usually uneventful, several significant complications may be encountered that may lead to maternal morbidity and mortality, especially primary postpartum haemorrhage. The objective of this study was to compare 400 ug oral misoprostol with 10 IU intramuscular oxytocin in the active management of the third stage of labour. METHODS This was a pr...

background: induction of ovulation in art is necessary for superovulation and the side effects of superovulatory drugs are debated. oxytocin as a natural hormone, have receptors and is synthesized by several reproductive organs. preovulatory presence of oxytocin receptor mrnas in granulosa cells indicating a role for oxytocin in follicular development. objective: the aim of the present study wa...

Nicolausyndrome or embolia cutis medicamentosa is a rare complication of intramuscular injection of some drugs. This syndrome has been reported after injection of NSAIDS, corticosteroids and antibiotics.Here we report a 16-year-old boy who developed this syndrome after intramuscular injection of benzathine penicillin.

The obesity pandemic can be viewed as a result of an imbalanced reaction to changing environmental factors. Recent research has linked circadian arrhythmicity to obesity and related diseases; however, the underlying mechanisms are still unclear. In this study, we found that high-fat diet (HFD) feeding strikingly promoted daytime rather than nighttime caloric intake in mice, leading to feeding c...

The aim of the present study was to investigate the effects of repeated injections of oxytocin on blood pressure and heart rate in spontaneously hypertensive rats (SHR). For this purpose subcutaneous (s.c.) injections of oxytocin 1 mg/kg or saline were given for 5 days to male and female SHR. Blood pressure and heart rate were measured daily before, during and after the oxytocin treatment perio...

a quasi experimental study was conducted in the labour rooms of one of the hospital's of the university of   medical science of iran, to compare the effect ofcord blood drainage and oxytocin injection into the umblicat   vein in the duration of the third stage of labour.   a total of 180 women in the course of normal pregnancies with no complications and normal vaginal   dd ivery were sele...

Objective To compare intramuscular oxytocin, Syntometrine® and carbetocin for prevention of postpartum haemorrhage after vaginal birth. Design Randomised double-blinded clinical trial. Setting Six hospitals in England. Population A total 5929 normotensive women having a singleton Methods Randomisation when birth was imminent. Main outcome measures Primary: use additional uterotonic agents. Seco...