background: the use of assisted reproductive technology (art) is increasing in the world. the rate, efficacy and safety of art are very different among countries. there is an increase in the use of intra cytoplasmic sperm injection (icsi), single fresh embryo transfer (et) and frozen-thawed embryo transfer (fet). objective: the objective of this study was to compare pregnancy rate in fresh et a...

introduction intra-articular injections of platelet rich plasma (prp) for the treatment of knee osteoarthritis have been shown to reduce pain and improve joint function. the aim of this study is to examine the joint function by adding intra-articular growth hormone to platelet rich plasma. this study was performed on the individuals with knee osteoarthritis and under ultrasound guidance. conclu...

OBJECTIVE Octreotide, a somatostatin analogue, has been shown to prevent angiogenesis in diverse in vitro models. We evaluated its effect on retinal neovascularization in vivo, using a neonatal rat retinopathy model. METHODS We used, on alternating days, hypoxia (10% O2) and hyperoxia (50% O2) during the first 14 days of neonatal rats, to induce retinal neovascularization. Half of the rats we...

The ocular toxicity of liposome-intercalated amphotericin B and commercial amphotericin B were compared after intravitreal injection in healthy pigmented rabbits. Ophthalmoscopic observations over 5 weeks following a single intravitreal injection showed vitreal band formation and focal retinal damage after doses of commercial amphotericin B as low as 5 micrograms. Such lesions were not seen in ...

Rationale. Neovascular glaucoma is the type of glaucoma most refractory to treatment. The most frequent causes are those associated with retinal hypoxia, which promotes the upregulation of the VEGF synthesis and produces fibrovascular membranes over the anterior chamber angle. Because the administration of anti VEGF products is still off label for neovascular glaucoma, there is not a single acc...

PURPOSE The purpose of the current study was to examine the ocular pathogenesis and immune reaction in mice after intravitreal dispase injection. METHODS Three microliters of dispase at a concentration of 0.2 U/μl were injected into the vitreal cavities of 4-6-week-old mice. Hematoxylin and eosin staining, immunofluorescence analysis, and electroretinograms of the eyes were then performed to ...

Aim of the present work has been to evaluate the effects in both the treated and the contra lateral eye of mono-lateral intra vitreal treatment with Ranibizumab (LUCENTIS®) in a 46-year-old woman affected by bilateral myopic choroidal neovascularization. A 46-year-old woman presented a best-corrected visual acuity of 8/10 in the right eye, and 1/20 in the left eye. Fundus examination revealed a...

abstract: introduction & objective: the infertility treatment by using in vitro matured oocyte has many potential applications. it minimizes the risk of ovarian hyper stimulation and is an alternative treatment for women with polycystic ovarian syndrome who may have problems regarding stimulation for ivf. this method may prove important for subjects in need of fertility preservation and also pr...