Since the birth of the first test-tube baby in 1978, Assisted Reproduction Techniques (ART) has been performed all over the world to alleviate human infertility. In 1991 with the advent of the Intra-Cytoplasmic Sperm Injection (ICSI) technique, a reasonable rate of male infertility cases due to severe oligospermia were successfully solved. However, several concerns about the safety and impact o...

Background: The role of embryo transfer (ET) in the success of in vitro fertilization/intra cytoplasmic sperm injection treatment is not well understood. In the present study we classified ET technique as difficult and easy types according to certain strict criteria, and compared the pregnancy outcome of

introduction: implantation of transferred embryos in the uterus after ivf_icsi cyclesis an important process that less information about it is available. zona hatching method is a suggested approach for this goal. the aim of this research is about performance of zona hatching by laser. methods: in this study 32 patients that enrolled had ivf/icsi cycles depend on inclusion criteria of study tha...

The aim of this report has been evaluating protamine content and DNA integrity of two patients with globozoospermia undergoing Intra Cytoplasmic Sperm Injection (ICSI). Semen analysis was carried out according to WHO criteria. Protamine deficiency and DNA fragmentation was assessed using Chromomycin A3 and sperm chromatin dispersion assay respectively. ICSI and chemical activation were carried ...

evidence suggests that human sperm chromatin anomalies adversely affect reproductive outcomes and infertile men possess substantially amount of sperm with chromatin anomalies than fertile men. routine semen analysis evaluates parameters such as sperm motility and morphology, but does not examine the nuclear dna integrity of spermatozoa. it has been suggested that altered nuclear chromatin struc...

background: there has been an increase in number of obese infertile females booked for advanced infertility treatment procedures like in vitro fertilization (ivf) and intra cytoplasmic sperm injection (icsi). the knowledge of impact of body mass index (bmi) on reproductive outcome can help to counsel these patients. objective: to compare reproductive outcome in females of different bmi after ic...

Evidence suggests that human sperm chromatin anomalies adversely affect reproductive outcomes and infertile men possess substantially amount of sperm with chromatin anomalies than fertile men. Routine semen analysis evaluates parameters such as sperm motility and morphology, but does not examine the nuclear DNA integrity of spermatozoa. It has been suggested that altered nuclear chromatin struc...

Surgical testicular sperm retrieval for intra-cytoplasmic sperm injection (ICSI) purposes is the only possibility of biological fathering in case of non-obstructive azoospermia (NOA). Successful retrieval only correlates with histology, not with FSH values or testicular volume. Concurrent AZFa and AZFb microdeletion predict unsuccessful recovery. Testicular sperm extraction (TESE) (mean of succ...