Hoarding is characterized by the persistent difficulty discarding or parting with possessions, regardless of the value others may attribute to these possessions. Hoarding resembles obsessive compulsive disorder (OCD) in several ways. The avoidance of and difficulties with discarding seem to be driven by fears of losing something significant or being responsible for a bad outcome. These could be...

introduction: tyrosine kinase inhibitors (tkis) were the first drugs to use an intracellular signaling molecule as a therapeutic target. unresponsiveness to tkis limits therapeutic options, making allogeneic hematopoietic stem cell transplantation (hsct) the only option leading to molecular remission. objectives: to characterize cml patients unresponsive to first- and/or second-generation tki t...

the spectrum of gluten related disorder might be much broader than currently believed. it is unknown why non-coeliac gluten sensitivity affects individuals at different ages. it is quite possible the triggering factors like infection might play an essential role in manifestation of this disorder. similar to secondary lactose intolerance, gluten intolerance might be a common occurrence behind pe...

Background: The prevalence of reported allergic diseases is higher in North-America than in other countries around the world. Further, certain types of allergies are more common in some geographic regions or amongst different ethnic populations. This phenomenon has not been well studied amongst the Persian population in the Canadian context; therefore, the current study aimed to compare the pre...

Background: A clear association between allergy and nasal polyposis (NP) is not determined and the role of food intolerance in patients with NP is not investigated by oral food challenge (OFC). Objective: To investigate the relation of salicylate food intolerance and atopy in patients with NP according to recurrence and aspirin sensitivity. Methods: A cross sectional multicenter study was d...

Impaired glucose tolerance has several adverse effects on growing fetus. In this study we evaluated the effect of excessive weight gain during pregnancy on the risk of glucose intolerance in pregnant women. A case-control study was conducted through which the glucose tolerance status after 100 gram oral glucose intake was compared between 60 pregnant women with maximum 10 weeks of gestation and...