نتایج جستجو برای: intestinal transit

تعداد نتایج: 150705  

Journal: :PloS one 2015
Ivana R Sequeira Roger G Lentle Marlena C Kruger Roger D Hurst

BACKGROUND Whilst the use of the mannitol/lactulose test for intestinal permeability has been long established it is not known whether the doses of these sugars modify transit time Similarly it is not known whether substances such as aspirin that are known to increase intestinal permeability to lactulose and mannitol and those such as ascorbic acid which are stated to be beneficial to gastroint...

Journal: :Gut 1999
D Sharpstone P Neild R Crane C Taylor C Hodgson R Sherwood B Gazzard I Bjarnason

BACKGROUND Diarrhoea in AIDS is associated with anorexia and weight loss. The importance of gastrointestinal transit in such symptoms has not been addressed. AIMS To assess jejunal to caecal transit times in subjects with AIDS related diarrhoea and weight loss and correlate these with measures of absorptive capacity and intestinal permeability. METHODS Jejunal to caecal transit times were a...

Journal: :Reproduction Nutrition Development 1994

Journal: :The Journal of physiology 2012
Meimin Xie Vijay R Kotecha Jon David P Andrade James G Fox Martin C Carey

Cholesterol gallstones are associated with slow intestinal transit in humans as well as in animal models, but the molecular mechanism is unknown. We investigated in C57L/J mice whether the components of a lithogenic diet (LD; 1.0% cholesterol, 0.5% cholic acid and 17% triglycerides), as well as distal intestinal infection with Helicobacter hepaticus, influence small intestinal transit time. By ...

Journal: :Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 1998
F A Gondim J R da-Graça G R de-Oliveira M C Rêgo R B Gondim F H Rola

We studied the effect of complete spinal cord transection (SCT) on gastric emptying (GE) and on gastrointestinal (GI) and intestinal transits of liquid in awake rats using the phenol red method. Male Wistar rats (N = 65) weighing 180-200 g were fasted for 24 h and complete SCT was performed between C7 and T1 vertebrae after a careful midline dorsal incision. GE and GI and intestinal transits we...

Journal: :International journal of clinical and experimental medicine 2015
Jun Song Jieyun Yin Jiande Chen

AIM This study was designed to compare the effects and mechanisms of transcutaneous electroacupuncture (TEA) on rectal distention (RD)-induced intestinal dysmotility with EA. METHODS six female dogs chronically implanted with a duodenal fistula, a proximal colon fistula and intestinal serosal electrodes were studied. EA and TEA were performed via needles and cutaneous electrodes placed at bil...

Journal: :Gut 1993
E K Yeoh M Horowitz A Russo T Muecke T Robb B E Chatterton

The effects of loperamide-N-oxide, a new peripheral opiate agonist precursor, on gastrointestinal function were evaluated in 18 patients with diarrhoea caused by chronic radiation enteritis. Each patient was given, in double-blind randomised order, loperamide-N-oxide (3 mg orally twice daily) and placebo for 14 days, separated by a washout period of 14 days. Gastrointestinal symptoms; absorptio...

Journal: :Gut 1996
D A Gorard J E Gomborone G W Libby M J Farthing

BACKGROUND Patients with anxiety and depression often have bowel symptoms. Until now, studies investigating a link between altered bowel habit and psychological illness have focused on patients with disturbed defecation presenting to gastroenterologists. AIMS To determine whether patients with anxiety and depression have objective evidence of abnormal intestinal transit irrespective of any bo...

Journal: :Cell reports 2013
Jarom Heijmans Jooske F van Lidth de Jeude Bon-Kyoung Koo Sanne L Rosekrans Mattheus C B Wielenga Marc van de Wetering Marc Ferrante Amy S Lee Jos J M Onderwater James C Paton Adrienne W Paton A Mieke Mommaas Liudmila L Kodach James C Hardwick Daniël W Hommes Hans Clevers Vanesa Muncan Gijs R van den Brink

Stem cells generate rapidly dividing transit-amplifying cells that have lost the capacity for self-renewal but cycle for a number of times until they exit the cell cycle and undergo terminal differentiation. We know very little of the type of signals that trigger the earliest steps of stem cell differentiation and mediate a stem cell to transit-amplifying cell transition. We show that in normal...

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