Timely and accurate evaluation of damage sustained by buildings after seismic events such as earthquakes or blasts is critical to determine the buildings’ safety and suitability for their future occupancy. Time used in conducting the evaluations substantially affects the duration for which the potentially damaged buildings remain unusable. The elapsed time may lead to direct economic losses to ...

the present study assesses the seismic performance of steel moment resisting frames (smfs) retrofitted with different bracing systems. two structural configurations were utilized: ordinary concentrically braces (ocbfs), buckling-restrained braces (brbfs). a 7-story and 18-story steel perimeter smfs were designed with insufficient lateral stiffness to satisfy code drift limitations in high seism...

A method is presented for extracting features of approximate optimal brace types and locations large-scale steel building frames. The frame subjected to static seismic loads, the maximum stress in members minimized under constraints on number braces each story interstory drift angle. new formulation important from machine learning results using a support vector with radial basis function kernel...

Innate defense regulators (IDRs) are synthetic immunomodulatory versions of natural host defense peptides (HDP). IDRs mediate protection against bacterial challenge in the absence of direct antimicrobial activity, representing a novel approach to anti-infective and anti-inflammatory therapy. Previously, we reported that IDR-1018 selectively induced chemokine responses and suppressed pro-inflamm...

We examined the effect of daunorubicin (DNR), the new anthracycline derivative idarubicin (IDR), and verapamil on two leukemia cell lines that displayed the multidrug resistant (MDR) phenotype and used laser flow cytometry to quantitate intracellular anthracycline content. The vinblastine-resistant human lymphoblastic leukemia cell line CEM-VBL demonstrated minimal DNR uptake; simultaneous incu...

The present study assesses the seismic performance of steel moment resisting frames (SMFs) retrofitted with different bracing systems. Two structural configurations were utilized: ordinary concentrically braces (OCBFs), buckling-restrained braces (BRBFs). A 7-story and 18-story steel perimeter SMFs were designed with insufficient lateral stiffness to satisfy code drift limitations in high seism...

IDR(s) is now recognized as one of the most effective methods, often superior to other Krylov subspace methods, for large nonsymmetric linear systems of equations. In this paper we propose an improvement upon IDR(s) by incorporating a higher-order stabilization polynomial into IDR(s). The proposed algorithm, named GBi-CGSTAB(s, L), shares desirable features with both IDR(s) and Bi-CGSTAB(L).

INTRODUCTION Innate defence regulator (IDR) peptides are synthetic cationic peptides, variants of naturally occurring innate immune effector molecules known as host defence peptides. IDR peptides were recently demonstrated to limit infection-associated inflammation selectively without compromising host innate immune functions. This study examined the impact of a 12-amino acid IDR peptide, IDR-1...

Innate defense regulator (IDR) peptides are a class of immunomodulators which enhance and modulate host innate immune responses against microbial pathogens. While IDR-mediated protection against a range of bacterial pathogens is dependent on enhanced monocyte recruitment to the site of infection, the mechanisms through which they increase monocyte trafficking remain unclear. In this study, anti...

Acute experiments on cats under chloralose anesthesia were designed to study the role of the brain stem in the transmission of the interhemispheric delayed response (IDR). Experiments on interaction of potentials recorded in brain stem and at cortex led to the conclusion that the IDR is relayed to the contra-lateral hemisphere via routes which pass through the general area of the mesencephalic ...