although globalization has created ample opportunities and spaces to share experiences and information, the diffusion of ideas, especially in global health, is primarily influenced by the unequal distribution of economic, political and scientific powers around the world. these ideas in global health are generally rooted in high-income countries (hics), and then reach low- and middle-income coun...

Purpose. To evaluate the efficacy of intravitreal melphalan for vitreous seeds from retinoblastoma in Chinese patients. Methods. This is a retrospective review of 17 consecutive Chinese patients (19 eyes) with viable vitreous seeds from retinoblastoma. The patients received multiple intravitreal injections of 20 ug melphalan. Results. The International Classification of Retinoblastoma groups we...

Purpose: To evaluate the effectiveness of chemoreduction (CRD) for globe saving in patients with intraocular retinoblastoma Methods: In this interventional case series all patients with intraocular retinoblastoma were included and classified according to the international classification of retinoblastoma (ICRB) from group A to E. Six cycles of intravenous Vincristine, Etoposide and Carboplatin ...

abstract objective: several studies have been published on the epidemiology of childhood malignancies worldwide. the primary objective of this study is to determine the relative frequency of pediatric cancers in iran. methods: using a retrospective approach, all confirmed cases of malignancies aged 14 years old or less at the time of first referral to the department of radiation oncology of jor...

PURPOSE Retinoblastoma is the most common primary malignant intra-ocular tumor in children. Although intra-arterial chemotherapy (IAC) by selectively infusing chemotherapy through the ophthalmic artery has become an essential technique in the treatment of advanced intra-ocular retinoblastoma in children, the outcome of IAC as primary therapy for infants less than 3 months of age remains unknown...

OBJECTIVE To describe tumor control following intra-arterial chemotherapy (IAC) for retinoblastoma. METHODS A retrospective interventional series in which 17 patients were treated with ophthalmic artery injection of melphalan, 5 mg, was undertaken to determine retinoblastoma control. RESULTS Of 190 children with retinoblastoma, 17 (9%) were treated with IAC. Catheterization was successful i...