Background. Exposure to prenatal inflammation increases the risk for development of bronchopulmonary dysplasia. Aim. To evaluate the correlation between cord blood and gastric aspirate levels of interleukine-6 (IL-6) and interleukine-8 (IL-8) in preterm infants, and lung function at the age of 8 years. Methods. Between 2000-2002 we recruited 129 infants of gestational age < 30 wks. The concentr...

BACKGROUND AND AIMS Recently, it has been demonstrated that the polymorphism 385 C->A of FAAH (fatty acid amide hydrolase) was associated with overweight and obesity. The aim of our study was to investigate the relationship of missense polymorphism (cDNA 385 C-A) of FAAH gene on obesity anthropometric parameters, cardiovascular risk factors and adipocytokines. METHODS A population of 279 fema...

Macrophages are specialized cells that control tissue homeostasis. They include non-resident and tissue-resident macrophage populations which characterized by the expression of particular cell surface markers secretion molecules with a wide range biological functions. The differentiation polarization macrophages relies on specific growth factors their receptors. Macrophage-colony stimulating fa...

the study of cytokines gene expression is quite important in various conditions of health and disease for the evaluation of clinical responses to new vaccination approaches. an absolute quantification is based on a calibration curve and production of standard controls to achieve more reliable results than in relative system. in this study we attempted to construct standard controls to evaluate ...

The study of cytokines gene expression is quite important in various conditions of health and disease for the evaluation of clinical responses to new vaccination approaches. An absolute quantification is based on a calibration curve and production of standard controls to achieve more reliable results than in relative system. In this study we attempted to construct standard controls to evaluate ...

pre-eclampsia is a pregnancy-specific syndrome that may be dangerous especially to the fetus. different cytokines have been found to be elevated in women with pre-eclampsia and may have possible roles in the development of this disorder. alleles of the interleukin-l-beta (il-lβ) and tumor necrosis factor alpha (tnf-α) genes are associated with pr-eeclampsia in several studies in different popul...

Systemic inflammation and elevated circulating levels of the endogenous nitric oxide inhibitor asymmetrical dimethylarginine (ADMA) have been associated with increased risk in cardiogenic shock (CS). In this prospective study, we assessed, over 4 consecutive days, the changes and possible associations between vascular function, markers of inflammation, and circulating ADMA levels in patients wi...