background: about 5–10% of patients with asthma suffer from poorly-controlled disease despite corticosteroid (cs) therapy. methods: 21 severe and 30 mild asthma patients were recruited and underwent collection of blood sample. we determined whether there were any differences in inflammatory biomarkers between severe and mild asthma patients or not.results: levels of interleukin-8 (il-8) and int...

background: use of smokeless tobacco in the form of moist snuff placed in the oral cavity is popular in rural india. the aim of the present cross-sectional study was to determine the effect of snuff on periodontitis by assessing interleukin (il)-1 β and il-8 levels in gingival crevicular fl uid. materials and methods: a total of 60 subjects were selected for this study. 40 subjects presented wi...

allergic asthma is a multifactorial disease, influenced by genetic and environmental factors. recent family-based studies have revealed evidence for linkage of human chromosomes 5q31-33, 12q15-24, 11q13 and 15q23.6 as regions likely to contain genes related to asthma. among the candidate genes in these regions are the genes encoding for human interleukin-4, interleukin-13 and interleukin-16. to...

This review aimed to describe the interleukins and interleukin gene polymorphisms related recommended as a RAS biomarker. Articles were searched through PubMed, ScienceDirect, Cochrane Library databases, using keywords of “Interleukin” AND “Recurrent Aphthous Stomatitis”. The Risk Bias Assessment tool for Non-randomized Studies (RoBANS) was used, writing this refers Preferred Reporting Items Sy...

objective(s): inflammation is an immune response toward injuries. although inflammation is healing response, but in some condition it will lead to chronic disease such as rheumatoid arthritis, inflammatory bowel disease, atherosclerosis, alzheimer’s and various cancer. indonesian cassia (cinnamomum burmanni c. nees & t. ness) known to contain coumarin, is widely used for alternative medicine es...

The aim of our study is to elucidate changes in the content pro-inflammatory interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) anti-inflammatory cytokines interleukin-10 (IL-10) blood serum guinea pigs dynamics experimental periodontitis immobilization stress.The combined pathology (experimental stress) accompanied by a pronounced progression proinflammatory group - TNF-α IL-6 against ba...

Idiopathic recurrent pericarditis (IRP) and adult-onset Still's disease (AOSD) are polygenic autoinflammatory diseases, in the pathogenesis of which pro-inflammatory cytokines from interleukin-1 superfamily play a central role. Aim . To compare serum concentrations proinflammatory glycosylated ferritin (GF) patients with IRP AOSD during an exacerbation. Material methods The study included 15 AO...

Introduction: Interleukin-2 (IL-2) as a T helper type 1 (Th1) cytokine has an important role Background and Objective: Interleukin-2 (IL-2) as a T helper type 1 (Th1) cytokine has an important role in activation, growth and differentiation of several immune cells. Moreover IL-2 is known as a pro-inflammatory and anti-tumoral cytokine. In addition deysregulation of IL-2 in some diseases such as ...