نتایج جستجو برای: interleukin 1 beta

تعداد نتایج: 2926902  

Journal: :Revista Brasileira de Farmacognosia 2023

Abstract Hydroxysafflor yellow A is extracted from Carthamus tinctorius L., Asteraceae, and has extensive pharmacological properties. In this study, interleukin-1 beta was used to establish the osteoarthritis model in vitro , impacts of hydroxysafflor on cell were analyzed. CCK8 measure viability, flow cytometry evaluate apoptosis reactive oxygen species. An enzyme-linked immunosorbent assay pe...

Journal: :Atlas of Genetics and Cytogenetics in Oncology and Haematology 2011

2017
Patrick L Stemkowski Agustin Garcia-Caballero Vinicius M Gadotti Said M’Dahoma Lina Chen Ivana A Souza Gerald W Zamponi

Abstract We recently reported that nerve injury or peripheral inflammation triggers an upregulation of the deubiquitinase, USP5 in mouse dorsal root ganglion and spinal dorsal horn. This leads to dysregulated ubiquitination of Cav3.2 T-type calcium channels, thus increasing Cav3.2 channel plasma membrane expression and nociceptive signaling in the primary afferent pain pathway. This phenomenon ...

Journal: :International Journal of Molecular Sciences 2018

Journal: :Journal of Experimental Medicine 1995

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