As the amount of knowledge bases (KBs) grows rapidly, the problem of question answering (QA) over multiple KBs has drawn more attention. The most significant distinction between multiple KB-QA and single KB-QA is that the former must consider the alignments between KBs. The pipeline strategy first constructs the alignments independently, and then uses the obtained alignments to construct querie...

Currently available alignment tools and procedures for marking-up alignments overlook non-contiguous multiword units for being too complex within the bounds of the proposed alignment methodologies. This paper presents the CLUE-Aligner (Cross-Language Unit Elicitation Aligner), a web alignment tool designed for manual annotation of pairs of paraphrastic and translation units, representing both c...

During the past decade, requirements within the US defence community for simulation-based tools to support acquisition, planning, (team) training and analysis, have resulted in a standard for distributed simulation known as DIS (Distributed Interactive Simulation). The potential advantages of distributed simulation technologies are evident: increased flexibility, building on existing software a...

This report describes an ATM Multipoint Connection Caching strategy (AMCC) to control the explosive growth of traffic within the network and at an endpoint in a large Distributed Interactive Simulation (DIS) application such as a battlefield simulation. For very large DIS applications with 100,000 entities, the current method of broadcasting information among entities will no longer be feasible...

SUMMARY Bellerophon is a program for detecting chimeric sequences in multiple sequence datasets by an adaption of partial treeing analysis. Bellerophon was specifically developed to detect 16S rRNA gene chimeras in PCR-clone libraries of environmental samples but can be applied to other nucleotide sequence alignments. AVAILABILITY Bellerophon is available as an interactive web server at http:...

Summary: The MSAViewer is a quick and easy visualization and analysis JavaScript component for Multiple Sequence Alignment data of any size. Core features include interactive navigation through the alignment, application of popular color schemes, sorting, selecting and filtering. The MSAViewer is ‘web ready’: written entirely in JavaScript, compatible with modern web browsers and does not requi...

MOTIVATION The power of multi-sequence comparison for biological discovery is well established. The need for new capabilities to visualize and compare cross-species alignment data is intensified by the growing number of genomic sequence datasets being generated for an ever-increasing number of organisms. To be efficient these visualization algorithms must support the ability to accommodate cons...

The development and maintenance of Concurrent Systems, Reactive Systems and Dynamic Systems, remain fraught with challenges attributable to factors such as: 1) the tendency of concurrently executing processes to interact in unforeseen ways; 2) the necessity for Reactive Systems to facilitate continuous interactions with their environments and; 3) the constantly changing internal states of Dynam...

We think of ontology matching as a dialogue-based interactive mediation process for which we propose a three stage model. A preliminary evaluation shows how we applied this method of eliciting input for ontology matching in the medical domain. Especially, we address the challenge how to use dialogue-based interactivity with the user to rate partial alignments between two ontologies.

Understanding how proteins mutate is critical to solving a host of biological problems. Mutations occur when an amino acid is substituted for another in a protein sequence. The set of likelihoods for amino acid substitutions is stored in a matrix and input to alignment algorithms. The quality of the resulting alignment is used to assess the similarity of two or more sequences and can vary accor...