sulfur mustard (sm, bis- (2-chloroethyl) sulphide) is a chemical warfare agent that causes dna alkylation, protein modification and membrane damage. sm can trigger several molecular pathways involved in inflammation and oxidative stress, which cause cell necrosis and apoptosis, and loss of cells integrity and function. epigenetic regulation of gene expression is a growing research topic and is ...

A modification of Moulines’ blind second order statistical Channel Subspace approach is proposed for the identification of single input multiple output finite impulse response channels. The modification exploits the transmitter redundancy introduced by a trailing zero filter bank precoder. The method is shown to be robust to common zeros and channel order over-estimation errors.

This paper presents methods for estimating time delay margin for adaptive control of input delay systems with almost linear structured uncertainty and a step input reference command signal. The bounded linear stability analysis method seeks to represent an adaptive law by a locally bounded linear approximation within a time window. The time delay margin of this input delay system represents a l...

We introduce Spectrally Matched Click synthesis as a novel application of FIR filter design allowing the creation of arbitrarily short duration clicks whose magnitude frequency spectra approximate those of arbitrary input sounds. We demonstrate its use on effects including incremental attack strength modification and continuous gradual “morphing” between any input sound and successively more im...

Optimization of geometry and surface modification of microchip input reservoirs were performed to achieve uninterferenced pressure-induced sample injection of multiple samples into microreactors using a single syringe pump. Nine samples of 3.5 microL were pipetted onto input reservoirs and loading of PCR mixture into 260 nL microreactors was achieved followed by successful PCR amplification, co...

Much research has shown that the voice source has strong influence on the quality of speech processing [4][5][6]. But in most of the existing speech modification algorithms, the effect of the voice source variation is neglected. This work explains why the existing modification scheme can’t truly reflect the voice source variation during pitch modification. We use synthesized voiced speech sound...

quantitative and model-based prediction of security in the architecture design stage facilitates early detection of design faults hence reducing modification costs in subsequent stages of software life cycle. however, an important question arises with respect to the accuracy of input parameters. in practice, security parameters can rarely be estimated accurately due to the lack of sufficient kn...

In this article we examine four objections to the genetic modification of human beings: the freedom argument, the giftedness argument, the authenticity argument, and the uniqueness argument. We then demonstrate that each of these arguments against genetic modification assumes a strong version of genetic determinism. Since these strong deterministic assumptions are false, the arguments against g...