PURPOSE OF REVIEW Long-acting antiretroviral (ARV) drugs may improve adherence to therapy and extend opportunities for therapeutic or prophylactic intervention to underserved patient populations. This review focuses on recent advances in the development of small molecule long-acting injectable ARV agents. RECENT FINDINGS The need for combination ART and physicochemical and dosing limitations ...

The injured central nervous system (CNS) can hardly regenerate. In vitro engineering of brain tissue hits technical bottlenecks. Also, the compaction and complexity anatomical structure defy accurate positioning for lesion sites in intracranial injuries. Therefore, repairing CNS remains a significant clinical challenge. Various recent vivo experiments have demonstrated excellent effect on nerve...

drug is an important and strategic commodity and a basic need of the people in all countries. the aim of this study is to determine the drug use patterns and descriptive analysis of prescriptions of doctors in ardabil city of iran. a retrospective study was carried out on 2000 randomly-selected prescriptions. data were obtained on demographics, prescribing indexes and analyzed by descriptive st...

We describe the design, development, analytical performance, and a limited clinical evaluation of 10-color Xpert MTB/XDR assay (CE-IVD only, not for sale in United States). This is intended as reflex test to detect resistance isoniazid (INH), fluoroquinolones (FLQ), ethionamide (ETH), second-line injectable drugs (SLIDs) unprocessed sputum samples concentrated sediments which are positive Mycob...

Medication errors are the cause of severe lesions and complications, particularly with regards to injectable medications.
 During anesthesia, several drugs administered simultaneously quite easily wrong medication may be administered, leading morbidity mortality. Different strategies have been devised reduce error, including use color letters facilitate identification various medications i...

Liposomes are tiny spheres ranging in diameters from 50 nm to several microns. The scope of this mini review is to introduce the concept of liposomes and to describe some aspects and mechanisms of stimulating topical and injectable products with liposomes. Two examples discussed in this article are topical delivery across skin and injectable formulations for anticancer drugs. Classic liposomes ...

INTRODUCTION: The use of injectable scaffolds has raised great interest as they minimise the need for invasive surgery and its associated complications, costs and discomfort to the patient. Furthermore, they can fill cavities of any size or shape as well as being able to deliver a localised therapeutic agent [1]. The aim of this study was to develop an injectable scaffold using PLGA micropartic...

Extensively drug resistant tuberculosis (XDR-TB) has recently emerged as a global health problem and pose a significant threat to TB control programmes. XDR-TB is caused by Mycobacterium tuberculosis resistant to at least isoniazid (INH), rifampin (RIF), any fluoroquinolone (FQs) and any of the three second line injectable drugs [amikacin, kanamycin (aminoglycosides) or capreomycin (polypeptide...