Both the process and synthesis of factors required for protein synthesis (or translation) account for a large proportion of cellular activity. In eukaryotes, the most complex and highly regulated phase of protein synthesis is that of initiation. For instance, across eukaryotes, at least 12 factors containing 22 or more proteins are involved, and there are several regulated steps. Recently, the ...

critical pedagogy (cp), as a poststructuralist educational movement, challenges the asymmetrical, power-over nature of classroom discourse and seeks to accommodate multivocality in the classroom and in the society. this study probed the discourse architecture of efl classrooms in iran. specifically, it aimed to explore to what extent iranian efl classrooms have stepped away from the teacher-dom...

Generally, the evaluation and assessment critical condition of rill formation are useful for a better understanding of soil erosion processes. The inherence characteristics of soils, which have much dynamic variations on the hill-slopes and are affected by rill formation, are the soil critical shear stress and soil erodibility factors. This study aims to assess experimental rill incision thre...

Shot peening beneficial effects on fatigue life of mechanical components are well known. However, there are some reports in the literature that indicate inappropriate shot peening parameters tend to reduce the fatigue life. It is therefore, the purpose of this study to find a logical quantitative justification for these observations. Using finite element method, a dynamic elastic-plastic simula...

Translation initiation is a key step for regulating the synthesis of several proteins. In bacteria, translation initiation involves the interaction of the mRNA with the ribosomal small subunit. Additionally, translation initiation factors 1, 2, and 3, and the initiator tRNA, also assemble on the ribosomal small subunit and are essential for efficiently recruiting an mRNA for protein biosynthesi...

Ribosomal protein S1, consisting of six contiguous OB-folds, is the largest ribosomal protein and is essential for translation initiation in Escherichia coli. S1 is also one of the three essential host-derived subunits of Qβ replicase, together with EF-Tu and EF-Ts, for Qβ RNA replication in E. coli. We analyzed the crystal structure of Qβ replicase, consisting of the virus-encoded RNA-dependen...

Background & aim: Early breastfeeding initiation (EBFI) defined as giving breast milk within the first hours following birth, which is recommended as a simple strategy for the enhancement of neonatal health and survival. This descriptive qualitative study was conducted to explore the practices, perceptions and beliefs of renowned traditional birth attendants (TBA) regarding EBFI in Chipinge rur...