background: acute opioid overdose is a common cause of admission in emergency department. in spite of the fact that naloxone is the main therapy for decades, there are controversies about the proper way of its use. this study aimed to compare two most recommended administration modes for naloxone. methods: in this single-blind clinical trial, 80 patients with methadone overdose syndrome were ra...

Liposomes are widely used as drug delivery systems in different forms including osmotic pumps, infusion and IV injection. In spite of these, there is no data available about their behavior under convective flow (e.g. infusion or osmotic pumps) and upon stagnation in such drug delivery systems. As a part of a series of investigations in this area, the present study investigates the effects of vi...

Abstract Liposomes are used widely as drug delivery systems in different forms including nanosuspensions, osmotic pumps, infusion pumps and IV injections. Some of these systems (e.g. infusion or osmotic pumps) might stay stagnant for a long time during or before administration, and therefore, might face phase separation. In spite of these, there is no data available about the behavior of lipos...

Abstract Liposomes are used widely as drug delivery systems in different forms including nanosuspensions, osmotic pumps, infusion pumps and IV injections. Some of these systems (e.g. infusion or osmotic pumps) might stay stagnant for a long time during or before administration, and therefore, might face phase separation. In spite of these, there is no data available about the behavior of lipos...

Since there is no detailed hospital based incident reporting system, this study was designed to evaluate the medication errors associated with infusion pumps in intensive care unit (ICU). The investigation was conducted in a Teaching hospital in the form of a prospective, observational study. A sample size of 43 doses administered to ICU patients was chosen to enable reliable estimate of error ...