نتایج جستجو برای: influenza virus
تعداد نتایج: 431493 فیلتر نتایج به سال:
Background and Aims: Each year, the influenza virus causes moderate to severe infections with a high prevalence throughout the world. Accordingly, an influenza vaccine that ensures protection with only a single dose would be a much more cost effective approach to influenza prophylaxis. Generation of Influenza non-replicating virus-like particles (VLP) in baculoviral expression system is an attr...
Background: The last two decades witnessed the spread of the first generation of influenza viruses. Influenza virosomes are promising tools in vaccine and immunotherapy programs because of their applications in various medical fields. The aim of the present study was to construct cationic virosomes derived from influenza virus using dialyzable detergent (DCPC) and cationic lipid (DOTAP) in vit...
Introduction: Influenza virus has several conserved peptides which have the capacity to be used as suitable candidates for appropriate and stable vaccine production against different types of influenza viruses. One of these peptides is HA2, the hemagglutinin stalk domain which mediates the membrane fusion and is conserved amongst different sub-types of influenza virus. This peptide is a good ca...
Background and Aims: Influenza A viruses are important pathogens for humans especially in pandemic episodes. Two adamantane derivates, amantadine and rimantadine, are used for prophylaxis and treatment of influenza A virus infections. However, single amino acid substitutions in the M2 transmembrane domain which lead to amantadine resistance of these viruses occur at residues 26, 27, 30, 31 or 3...
Influenza is a highly contagious zoonotic disease in the world. Avian H9N2 influenza virus is a significant pandemic pathogen widely distributed throughout the world. Pet ownership has been documented as a risk factor for infection transmission to human. Considering major public health concern, the prevalence of antibodies against avian H9N2 influenza virus was evaluated in 170 serum samples of...
conclusions the prevalence of pandemic influenza viruses in recent years has caused financial losses as well as mortalities around the world. this shows the importance of the rapid diagnosis of common serotypes in our society. using real-time rt-pcr is recommended for the early diagnosis and the rapid identification of the individuals infected with pandemic influenza virus. background timely di...
results out of 253 cases confirmed for influenza a (h1n1), 9 women and 11men had died. amongst these cases the minimum and maximum age was3.5 and90 years, respectively. also, from the 20 confirmed cases of influenza a (h1n1) that had died, 16 cases had at least one underlying disease. conclusions there was no significant association between mortality of confirmed cases of influenza a (h1n1) and...
Avian influenza H9N2 subtype viruses have had a great impact on Iranian industrial poultry production economy since introduction in the country. To approach Rapid and precise identification of this viruses as control measures in poultry industry, a real time probe base assay was developed to directly detect a specific influenza virus of H9N2 subtype -instead of general detection of Influenza A ...
Introduction: Influenza A virus causes unpredictable epidemics and pandemics by creating antigenic variations. With the appearance of each new strain, rapid emergency countermeasures are taken against this new strain. Hence, designing an applicable and cross protective strategy to counter this virus is of great importance. To achieve this, choosing conserved antigenic regions in influenza virus...
Introduction: Avian influenza viruses are considered as a serious threat to human and animal health. An increase in expression of proinflammatory cytokines and type I IFN genes, as well as host cell death responses contribute to the pathogenesis of influenza infection. Hence, this study aimed to evaluate the growth dynamics of subacute avian influenza virus in human respiratory alveolar epithel...
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