This review aimed to describe the interleukins and interleukin gene polymorphisms related recommended as a RAS biomarker. Articles were searched through PubMed, ScienceDirect, Cochrane Library databases, using keywords of “Interleukin” AND “Recurrent Aphthous Stomatitis”. The Risk Bias Assessment tool for Non-randomized Studies (RoBANS) was used, writing this refers Preferred Reporting Items Sy...

BACKGROUND Enoxaparin, a mixture of anticoagulant and non-anticoagulant fractions, is widely used as an anticoagulant agent. However, it is also reported to possess anti-inflammatory properties. Our study indicated that enoxaparin inhibits the release of IL-6 and IL-8 from A549 pulmonary epithelial cells. Their release causes extensive lung tissue damage. The use of enoxaparin as an anti-inflam...

Oncogene-induced cellular senescence (OIS) is emerging as a potent cancer-protective response to oncogenic events, serving to eliminate early neoplastic cells from the proliferative pool. Using combined genetic and bioinformatic analysis, we find that OIS is linked specifically to the activation of an inflammatory transcriptome. Induced genes included the pleiotropic cytokine interleukin-6 (IL-...

Background In 1980’s, several case reports emerged implying that administration of corticosteroids for fetal maturation in pregnancies complicated by HELLP syndrome may be followed by improvement in clinical and laboratory markers. It has been hypothesized that the underlying mechanism for such observations resides in the antiinflammatory and immunosuppressive effects of corticosteroids. Preecl...

objective(s): intestinal ischemia-reperfusion is a major problem, which may lead to multiorgan failure and death. the aim of this study was to evaluate the protective effects of dexmedetomidine on cell proliferation, antioxidant system, cell death, and structural integrity in intestinal injury induced by ischemia-reperfusion in rats. materials and methods: animals were randomized into three gro...

BACKGROUND Cardiopulmonary bypass induces a nonspecific inflammatory response. Procalcitonin has been advocated as a specific biomarker for infection. The authors studied the accuracy of procalcitonin to diagnose postoperative infection after cardiac surgery and compared it with those of C-reactive protein, white blood cell count, and interleukins 6 and 8. METHODS The authors prospectively in...

background sepsis can be defined as the body’s response to an infection. sepsis in children remains a significant cause of morbidity and mortality worldwide. objectives this study focuses on the etiological factors, risk factors, and clinical characteristics of sepsis in neonate and pediatric patients. patients and methods a prospective study was conducted over a six-month period in the pediatr...

Choroidal neovascularization (CNV) is a common and severe complication in heterogeneous diseases affecting the posterior segment of the eye, the most frequent being represented by age-related macular degeneration. Although the term may suggest just a vascular pathological condition, CNV is more properly definable as an aberrant tissue invasion of endothelial and inflammatory cells, in which bot...

Bovine mastitis is a disease that concerns animals' welfare and increases the economic production losses. Bacterial agents such as Staphylococcus species are main causative agent of bovine mastitis. This bacterial expresses some inflammatory cytokines might enhance cell-mediated, which may promote pathogenesis The objective current study was to investigate innate immune response circulating lev...

Hospital-acquired pneumonia is a common cause of mortality in intensive care units. Therapy effectiveness depends on the antibiotic regimen chosen. Serum cytokines concentrations could be used as sensitive predictors hospital-acquired outcomes and therapy response. Analysis literature Pubmed database shows, that using key terms “pneumonia”, “cytokines” “biomarkers”, 1062 publications can found....