oral lichen planus is diagnosed according to clinical and histopathological characteristics.some times all of the classical  histopathological features can not be seen.in some articles the presence of mast cells have been noted below the epithelium of oral lichen planus patients.the following study was done to evaluate the number of mast cells in the histopathological sections of 20 oral lichen...

BACKGROUND Oral lichen planus (OLP) is an autoimmune disease produced by T lymphocyte attack on basal epithelial cells. OLP can undergo malignant transformation that may be linked to an increased proliferative activity and decreased apoptosis rate of the epithelial cells, phenomena that may be influenced by the inflammatory infiltrate. The objectives of this study were to assess the quantitativ...

Recently, we published the first validated index to assess histological disease activity in UC. We believe that some clarifications have to be made regarding the assessment of this index in both clinical practice and clinical trials. Three histological criteria have to be assessed. The first criterion is the presence of mucosal ulceration defined by the loss of colonic crypts replaced with ‘imm...

There are a limited number of studies correlating the different stages of dendritic cells (DC) maturation with cytokines in individuals presented chronic periodontitis (CP). The aim of the study was to evaluate the correlation among the expression of IL-2, IL-10, IL-4, IL-6, IFN-γ, TNF-α, and IL-17A with the presence of DC and mild-moderate or advanced CP. Gingival samples were obtained from 24...

background thermal injury is associated with several biochemical and histopathological alteration in tissue. analysis of these objective parameters in research and clinical field are common to determine healing rate of burn wound. negative pressure wound therapy has been achieved wide success in treating chronic wounds. this study determines superficial burn wound healing with intermittent nega...

background and objective: rosacea is a common and ill-defined disease and demodex folliculorum has been reported in rosacea in a number of clinical studies. since demodex mite is present in many healthy individuals, the mite may have a pathogenic role only when it is present in high densities. therefore, in this study, the possible role of demodex folliculorum and the importance of mite density...

Background and Objective: Rosacea is a common and ill-defined disease and Demodex folliculorum has been reported in rosacea in a number of clinical studies. Since demodex mite is present in many healthy individuals, the mite may have a pathogenic role only when it is present in high densities. Therefore,...

Metalloproteinase-9 (MMP-9) is the proteolytic enzyme degrading type IV collagen, and plays important role in the invasiveness and metastatic potential of tumor cells. The aim of the current study was to compare the association between the intensity of MMP-9 expression in neoplastic cells and in the interstitial inflammatory infiltrate cells in esophageal cancer with clinicopathological feature...