Normal wound healing in adults follows an ordered progression of events, which ultimately results in wound closure. In some cases, however, wound closure may not occur. There are many reasons why a wound will fail to heal, including both local (e.g. the presence of a foreign body or infection) and systemic (e.g. malnutrition or diabetes) factors. In a slow-healing or non-healing wound, it is im...

Foot ulcers increase morbidity and mortality in diabetic patients. Due to poor healing factors, surgical wound healing is questionable in diabetic patients. We report a patient with insulin-dependent diabetes mellitus, sensory neuropathy and microangiopathy, who had an infected stump of the right three middle digits and subsequent transmetatarsal amputation. The infected postoperative ulcer was...

Restoration of lung homeostasis following injury requires efficient wound healing by the epithelium. The mechanisms of lung epithelial wound healing include cell spreading and migration into the wounded area and later cell proliferation. We hypothesized that mechanical properties of cells vary near the wound edge, and this may provide cues to direct cell migration. To investigate this hypothesi...

Methods Baseline assemnet made on wound infection rate of 100 patients before the impelemenation of hand hygiene using the WHO accreditted alcohol based hand rub technique. Six monthe after, surgical site wound infection in 100 pateints of similar profile is reaudited. Wound infection is declared if there are clinical signs of wound infection from day 3 on post operative course. Wounds already ...

This study evaluated the wound healing potential of Spathodea campanulata stem bark in Sprague Dawley rats using the excision wound model. The methanol extract contained glycosides, flavonoids and tannins, and was relatively stable when stored at the room temperature for six (6) months. Solvent-free, semi-solid extract of S. campanulata was incorporated into an aqueous cream and applied (10 % w...

Acute infection of surgical incision sites often requires specialized wound care in preparation for surgical closure. Optimal therapy for preparing such wounds for a secondary closure procedure remains uncertain. The authors report wound outcomes after administering acoustic pressure wound therapy in conjunction with negative pressure wound therapy with reticulated open-cell foam dressing chang...

Infected urachal cysts are a rare clinical manifestation in adults. We present the case of a female patient with an infected urachal cyst, discuss the embryology, clinical presentation, diagnostics and the therapeutic procedure and make a comparison with the literature.

Wound dressings represent a part of the management of diabetic foot ulceration. Ideally, dressings should alleviate symptoms, provide wound protection, and encourage healing. No single dressing fulfills all the requirements of a diabetic patient with an infected foot ulcer. Dressings research in this area is generally poor. However, each category of dressings has particular characteristics that...