Background Infantile colic is a painful phase in the first months of infancy but no safe and effective conventional treatment exists. Massage is used in traditional medicine as a control and treatment method for infantile colic. The aim of this study is to evaluate the efficacy and safety of massage in the control and treatment of infantile colic. Materials and Methods We searched international...

Congenital erythropoietic porphyria is a rare autosomal recessive disorder of porphyrin metabolism in which the genetic defect is the deficiency of uroporphyrinogen III cosynthase (UIIIC). Deficiency of this enzyme results in an accumulation of high amounts of uroporphyrin I in all tissues, leading to hemolytic anemia, splenomegaly, erythrodontia, bone fragility, exquisite photosensitivity, and...

History and development of the profession: ∑ History and development of the profession of SpeechLanguage Pathology (SLP) specifically in Nepal, neighboring countries and abroad. ∑ Major work activities of the SLP. ∑ Various settings of speech – language therapy service delivery. ∑ Professions concerned with communication disorders. Human communication: ∑ Definitions and components. ∑ Interdepen...

The mode of presentation, clinical course, and outcome of 12 infants with cystic fibrosis and liver disease referred over an 18 year period were investigated retrospectively. Median age at presentation was 6.5 weeks (range, 5-12). Two thirds were boys. Conjugated hyperbilirubinaemia was the presenting symptom in 11 patients, and hypoalbuminaemia in one. Jaundice was cleared over a median period...

The plant Pergularia daemia has been traditionally used as anthelmintic, laxative, antipyretic expectorant and also used to treat infantile diarrhea and malarial intermittent fevers. It is widely distributed in the tropical and sub tropical regions of the world. Various phytochemical including terpenoid, flavonoids, sterols and cardenolids have been isolated and identified from the various part...

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introduction: infantile colic is one of the most common problems in the family in few weeks after birth. pathophysiology of colic has not been explained yet. the aim of this study was to compare the intestinal microflora in colicky and non-colicky infants. materials and methods: seventy breastfed infant aged 15-60 days were enrolled in this study and divided into two groups of 35 colicky and no...

AIM Hepatobiliary scintigraphy is an integral part in the diagnostic work-up of the neonatal cholestasis syndrome. However, less than optimal specificity is its major disadvantage. Differentiation between biliary atresia and neonatal hepatitis is nearly impossible in some cases with poor hepatocellular function. 99mTc sestamibi (MIBI) is a cationic lipophilic agent which is a substrate of P-gly...

BACKGROUND Niemann-Pick disease type C (NP-C) is a rare neurovisceral disease characterized by progressive neurodegeneration and premature death. We report data recorded at enrolment in an ongoing international NP-C registry initiated in September 2009 to describe disease natural history, clinical course and treatment experience of NP-C patients in clinical practice settings. METHODS The NPC ...

background: hyperbilirubinemia, or jaundice, is a life threatening disorder in newborns. it is a multifactorial disorder with many symptoms. generally, the physiological jaundice is the most prevalent type however in some regions pathological jaundice is also common. this review article focuses on a brief introduction to jaundice, its types and causes, measuring the bilirubin level, clinical ap...