The objective of this study was to develop vaginal suppository containing lactobacillus. Four kinds of vaginal suppositories containing Lactobacillus paracasei HL32 were formulated: 1) a conventional suppository with Witepsol H-15 as a base, 2) a conventional suppository with mixed polyethylene glycols (PEGs) as a base, 3) a hollow-type suppository with Witepsol H-15 as a base and 4) a hollow-t...

Three cases of nephrotic syndrome treated by indomethacin, either oral capsules or rectal suppositories, are presented. Results showed that indomethacin caused marked reduction in proteinuria and frequency of micturition, loss of oedema fluid and elevation of serum albumin and total protein. These effects were continued after withdrawal of indomethacin in two patients. It could be concluded tha...

The suitability of apparatuses for the quality control of indomethacin (IND, 50 mg) compounded suppositories was evaluated and the effects of the type of suppository base on release profiles was investigated. The release characteristics of hydrophilic and lipophilic suppositories containing IND were compared using four types of dissolution methods: basket (RB), paddle (PD), dialysis tubing (DT)...

Goreisan suppository is prepared as a hospital preparation, and successfully used for the treatment of diarrhea and vomiting in young children with common cold. While clinical efficacy of the suppository has been reported, few studies have been carried out to clarify the preparation procedure and pharmacokinetics of the suppository. In this study, trans-cinnamic acid (CA) was used as a represen...

hands. Rheumatoid arthritis was diagnosed and she was treated with phenylbutazone, indomethacin suppositories, and gold injections. A tense swelling developed behind the right knee 6 months later. She was referred to a general surgeon and an initial diagnosis of fibrosarcoma was made. However, at operation, a synovial popliteal cyst was found and removed. After this, synovial fluid began to lea...

suffering from febrile convulsions. Previous studies of clinical applications of rectal DZP have shown that intermittent administration of DZP suppositories during the febrile period prevents recurrent febrile convulsions. In addition to DZP suppository, acetaminophen (AAP) suppositories are occasionally used to ease suffering by high fever. However, the simultaneous combination of DZP and AAP ...

A traditional Chinese herbal medicine, Kampo medicine, maoto, has been widely used in the treatment of febrile symptoms caused by viral infection. This herbal extract granule for oral use, however, is not well accepted by infants or young children due to its unpleasant taste and odor. Therefore, we prepared Kampo medicine, maoto, suppository and investigated the pharmaceutical and clinical effi...

Introduction: Parikartika is most common ano-rectal disorder. The text of parikartika mentioned in Samhitas. In this disease there are symptoms such as bleeding per rectum, hard stools, burning sensation around anal region. trial, group A (n=30) included Palashadigudavarti, whereas B Diclofenac sodium suppository for administration over (acute fissures). Gandharva haritaki choorna acts laxative...

BACKGROUND The postoperative analgesic effects of rectal indomethacin and tramadol were compared in patients undergoing elective termination of first trimester pregnancy and diagnostic dilatation and curettage. METHODS Eighty-one American Society of Anesthesiologists class I and II women undergoing first trimester termination of pregnancy or diagnostic dilation and curettage were randomly all...