-The modification of the gut microbiota with new feed additives such as probiotics, prebiotics toward host protection is to support animal health. Out of these probiotics, prebiotics are widely used. Genomic knowledge about gut microbiota as well as its deviations will advance the selection of new and specific probiotics. The suitable combination probiotics, prebiotics decrease the risk of inte...

BACKGROUND & AIMS We tested whether the attenuation of experimental colitis by live probiotic bacteria is due to their immunostimulatory DNA, whether toll-like receptor (TLR) signaling is required, and whether nonviable probiotics are effective. METHODS Methylated and unmethylated genomic DNA isolated from probiotics (VSL-3), DNAse-treated probiotics and Escherichia coli (DH5 alpha) genomic D...

Clostridium difficile is one of the most important and widespread causes of acute gastroenteritis. Due to the limitations of current therapeutic options there is a need for the development for new treatment methods. Probiotics are an alternative treatment option that have gained prominence in the last few years, and the ability of various probiotics to mitigate C. difficile infection was tested...

Weaning during infancy refers to the initiation of complementary food to breast milk. During weaning, there are significant changes on the gastrointestinal microbiota. Deleterious alterations of the gastrointestinal microbiota can result in pathological processes while measures that stimulate its development and stability, like the use of probiotics, are beneficial. The mechanisms by which prob...

OBJECTIVE To perform a pilot project to determine if this research design was appropriate to explore potential causal relationships between oral probiotic use and vaginal Group B Streptococcal (GBS) colonisation rates in pregnant women. METHOD Thirty-four GBS-positive women at 36 weeks pregnant were recruited. The participants were randomly allocated to the control group, who received standar...

The use of probiotics and synbiotics in the prevention and treatment of different disorders has dramatically increased over the last decade. Both probiotics and synbiotics are well known ingredients of functional foods and nutraceuticals and may provide beneficial health effects because they can influence the intestinal microbial ecology and immunity. The present study reviews the effects of pr...

Probiotics are defined as microbial food supplements which beneficially affect the host animal by improving its intestinal microbial balance. The probiotics were improved feed conversion for the target species, reduced morbidity or mortality and benefits for the consumer through improved product quality. In this study, we found that a combination of probiotics with different mechanisms of actio...

Probiotics are dietary supplements containing potentially beneficial bacteria or yeasts. Probiotics are live microorganisms thought to be beneficial to the host organism and, when administered in adequate amounts, confer a health benefit on the host. Lactic acid bacteria and bifidobacteria are the most common types of microbes used as probiotics. Probiotics strengthen the immune system to comba...

Oxidative stress defines a condition in which the prooxidant-antioxidant balance in the cell is disturbed, resulting in DNA hydroxylation, protein denaturation, lipid peroxidation, and apoptosis, ultimately compromising cells' viability. Probiotics have been known for many beneficial health effects, and the consumption of probiotics alone or in food shows that strain-specific probiotics can pre...