OBJECTIVES To estimate the cumulative incidence for the development of diabetes mellitus in Chinese women with persistently impaired glucose tolerance after gestational diabetes, and evaluate putative risk factors. DESIGN Historical cohort study. SETTING A regional hospital in Hong Kong. PATIENTS Women with postpartum impaired glucose tolerance (as confirmed by a 75-gram oral glucose tole...

BACKGROUND Biomarkers for estimating reduced glucose tolerance, insulin sensitivity, or impaired insulin secretion would be clinically useful, since these physiologic measures are important in the pathogenesis of type 2 diabetes mellitus. METHODS We conducted a cross-sectional study in which 94 individuals, of whom 84 had 1 or more risk factors and 10 had no known risk factors for diabetes, u...

The classification of abnormalities of glucose tolerance introduced in 1979 by the National Diabetes Data Group and agreed by the World Health Organisation included the category of impaired glucose tolerance.' 2 The diagnosis depends on the blood glucose concentration two hours after a glucose load being above normal (6-7 mmol/l) and below the new diabetic value (10 mmol/l). This category satis...

abstract background the aim of the present study was to determine the endocrine dysfunction in patients with major thalassemia, who receive hyper transfusion. materials and methods this cross sectional study was performed during one year, which included 65 major thalassemia patients (31 females and 34 males), aged between 14 month to 27 years old (median 10,3). growth assessment was measured by...

BACKGROUND AND PURPOSE The purpose was to assess the prevalence of disorders of glucose metabolism and insulin resistance in Japanese ischemic stroke patients with no history of diabetes by performing 75-gram oral glucose tolerance test (OGTT). METHODS We recruited 427 ischemic stroke patients (atherothrombotic infarction, n=220; lacunar infarction, n=125; cardioembolic infarction, n=82). OGT...

To the Editor: Tamita et al reported that abnormal glucose tolerance in patients with acute myocardial infarction (AMI) is a major risk factor for future cardiovascular events and might critically distinguish high-risk individuals.1 The cardiovascular event-free survival rate in the impaired glucose tolerance (IGT) group and the group with newly diagnosed diabetes were 73% and 67%, respectively...

T ype 2 diabetes is now epidemic. In the U.S., there has been a 61% increase in incidence between 1990 and 2001 (1). There are currently 1.5 million new cases per year, and the prevalence in 2005 was almost 21 million (2). The epidemic has affected developed and developing countries alike, and the worldwide prevalence of diabetes is projected to increase dramatically by 2025 (3). The increase i...