: It is widely believed that stress suppresses immune function and increases susceptibility to infections and cancer. Paradoxically, stress is also known to exacerbate allergic, autoimmune, and inflammatory diseases. These observations suggest that stress may have bidirectional effects on immune function, being immunosuppressive in some instances and immunoenhancing in others. It has recently b...

................................................................................................. 2 Introduction Hormone replacement............................................................................ 3 Encapsulation of cells........................................................................ 4 Problem statement...........................................................................

Using the predictive algorithm of Rothbard and Taylor (1988 . EMBOJ. 7:93) and the primary structure of gp63 (Button, L., and M.R . McMaster. 1988 . J. Exp. Med. 167:724 ; Miller, R.A., S.G . Reed, and M. Parsons . 1990 . Mol. Biochem. Parasitol. 39:267) we have been able to delineate the structures of a number of gp63 T-cell epitopes which stimulate the proliferation of CD4' cells . One of the...

Diabetes, a large and growing worldwide health concern, affects the functional mass of the pancreatic beta cell, which in turn affects the glucose regulation of the body. Successful transplantation of cadaveric islets and pancreata for patients with uncontrolled type 1 diabetes has provided proof-of-concept for the development of commercial cell therapy approaches to treat diabetes. Three broad...

The aim was to ascertain any possible linkage between humoral immune responses to principal biomarkers (α-synuclein monomers, its toxic oligomers or fibrils, dopamine and S100B) and cellular immunity in Parkinson's disease development. There were elevated autoantibody titers to α-synuclein monomers, oligomers plus fibrils in 72%, 56%, and 17% of Parkinsonian patients respectively with a 5-year ...

Abstract Purpose of Review Here, we review the use cell sheet technology using different types and its potential for restoring extracellular matrix microenvironment, perfusion, immunomodulatory action on islets beta cells. Recent Findings Cell sheets can be produced with fabrication techniques ranging from widely used temperature responsive system to magnetic system. A variety cells have been p...