The immunologic surface markers on guished from benign lymphocytosis by surlymphocytes and clinical characteristics of face marker criteria. In untreated CLL, sur35 patients with established ( stages 0-4) face marker characteristics are stable with CLL with absolute lymphocyte counts time and predominantly reflect expansion > 1 5,000/cu mm were compared to those of clones expressing only B cell...

Neoplastic lesions of the kidney and certain other organs are sometimes associated with increased erythropoietin and/or erythrocytosis in man and experimental animals. It seems likely that measurement of erythropoietin, although not specific, could be helpful in detecting renal neoplasms and in following the progress of treated tumors of the kidney and certain other organs. Increasing the sensi...

Expression of the macrophage mannose receptor is inhibited by interferon gamma (IFN-gamma), a T helper type 1 (Th-1)-derived lymphokine. Interleukin 4 (IL-4), a Th-2 lymphocyte product, upregulates major histocompatibility class II antigen expression but inhibits inflammatory cytokine production by macrophages. We have studied the effect of IL-4 on expression of the macrophage mannose receptor ...

BACKGROUND Proper treatment of lymph node-negative breast cancer depends on an accurate prognosis. To improve prognostic models for this disease, we evaluated whether an immunohistochemical marker for proliferating cells, Ki-S2 (a monoclonal antibody that binds to a 100-kd nuclear protein expressed in S, G2, and M phases of the cell cycle), is an accurate indicator of prognosis. METHODS We st...

Background and aim: Asthma is a chronic inflammatory airway disease mediated by immunologic mechanisms. The pathogenic role of immunoglobulin E (IgE) always associated with the development allergic diseases, especially asthma because it highly responsive to allergen. present study aimed estimate compare total serum IgE levels in mild, moderate, severe asthmatics healthy controls (HC) obtain rel...

cow’s milk allergy (cma) is the most frequent food allergy in children and oral immunotherapy (oit) is a promising approach for treatment of patients. the most challenging cases are anaphylactic with coexisting asthma and proposing safe protocols is crucial especially in high risk groups. considering that cma varies among patients, an individualized oit protocol would be beneficial to achieve a...

cytotoxic effects of obturation materials were tested in presence and absence of endotoxin on human monocytes in vitro.human monocytes from thp-1 cell line were cultured. three millimeters from the tip of each resilon and gutta percha points were cut and directly placed at the bottom of the culture wells. cultured cells were exposed to gutta percha (groups g1 and g2) and resilon (r1 and r2). te...

Abstract The spleen is the most commonly injured organ in blunt abdominal trauma. Patients with these injuries are increasingly being managed nonoperatively, use of Splenic Artery Embolisation (SAE). Many patients receive lifelong prophylactic antibiotics as though they were asplenic. aim to seek robust evidence splenic vascular integrity and immunocompetence following SAE, consider whether ant...