Partially purified high molecular weight preparations of phytochrome, estimated to be close to 440,000 molecular weight based upon chromatography through a calibrated Bio-Gel P-300 column, were obtained from Garry and Newton oats (Avena Sativa L., cv. Garry and cv. Newton), rye (Secale cereale L., cv. Balbo), barley (Horedum vulgare L., cv. Harrison), and pea (Pisum sativum L., cv. Alaska) by a...

‡ MRC Immunochemistry Unit, Department of Biochemistry, University of Oxford, South Parks Road, Oxford, UK. OX1 3QU ‡‡ Institute of Infection, Immunity & Inflammation, University of Nottingham, Queen's Medical Centre, Nottingham, UK. NG7 2RD ¶ To whom correspondence may be addressed: MRC Immunochemistry Unit, Department of Biochemistry, University of Oxford, South Parks Road, Oxford, UK. OX1 3Q...

Immunochemistry is now an established ancillary technique in lung cancer diagnosis. Not only does it help in supporting the morphological diagnosis of malignancy, but its role now extends to the determination of cell lineage, ascertaining the primary site of tumour origin and contributing to decisions on prognosis and treatment. Early detection and confirmation of lung cancer facilitate early t...

In the February 15th issue of Cancer Research, Kao et al. (1) report findings on Pgp and MRP expression in relation to sestamibi scintimammography. As “it is difficult to extract RNA from surgical breast specimen embedded and maintained in Tissue-Tek OCT,” they analyzed Pgp and MRP expression only by IHC. We have conducted a similar study on 30 patients with large breast cancer before neoadjuva...

IN the first paper of this series [Clutton et al. 1937] a method was described by which simple carbohydrate residues could be introduced into a protein in the form of the O-fl-glycoside of tyrosine, the latter being coupled in peptide linkage with the free amino groups of the protein molecule. Application of this method to the preparation of O-fl-glucosidotyrosylgelatin was described and it was...