objective(s): the effect of prolonged overtraining on cytokine kinetics was compared with moderate exercise in the present study.   materials and methods: male wistar rats were randomly divided into control sedentary (c), moderate trained (mt), (v=20 m/min, 30 min/day for 6 days a week, 8 weeks), overtrained (ot) (v=25 m/min, 60min/day for 6 days a week, 11 weeks) and recovered overtrained (or)...

exposure to high dosages of sulfur mustard (sm) can cause bone marrow depression, immune system suppression, impairment of the immune functions, and eventually results in diseases due to secondary immune disorders. in this article, we have studied the effects of this poison on iranian veterans by analysis of related published studies. in a systematic search, the effects of sm gas on iranian vic...

the radiation-induced bystander effect is the phenomenon which non-irradiated cells exhibit effects along with their different levels as a result of signals received from nearby irradiated cells. responses of non-irradiated cells may include changes in process of translation, gene expression, cell proliferation, apoptosis and cells death. these changes are confirmed by results of some in-vivo s...

external exposed radiation may play an important role in pathogens of irritable bowel syndrome (ibs), although is thought to arise due to a combination of genetic and environmental factors. the result is dysregulated immune responses due to alteration in the gut microbiota population and the subsequent development of gut inflammation. it has recently been shown that the effect of ionizing radia...

background & aim: in present study, some of the iranian endemic medicinal plants were used to evaluate potential as well as therapeutic agent and immunostimulants in aquaculture. the essential oils of five species from leaves and inflorescence were used to determinate the effects on immune system in rainbow trout (oncorhynchus mykiss). experimental: the experimental in a completely randomiz...

the aim of this study was to evaluate the effect of organic selenium supplementation on the immune response of broilers vaccinated against coccidiosis, infection bursal disease virus (ibdv) and newcastle diseases virus (ndv). the study included three treatments (t), t1= control (inclusion of inorganic selenium in a basal diet), t2= basal diet + 0.2 ppm of organic selenium as selenomethionine an...

it has been suggested that prf might possibly have an effect on the immune cells. we considered using the intravenous route to apply prf in conditions that are caused by an unresolved immune action or connected to allostatic load, implicating an abnormally reacting immune system to obtain a systemic effect that could possibly be an additional tool in treating some of these conditions. these man...

restraint-induced stress (rs) increases histamine concentration in the brain. there is no previous report regarding the role of histamine receptors in immunomodulatory effect of rs. in the present study the role of brain histamine receptors on reduction of humoral and cellular immune function induced by rs was evaluated. for this purpose male wistar rats (200-250 g) were immunized with sheep re...

introduction: hepatitis c virus (hcv) infection is a major public health problem which influences about 170 million people worldwide. different types of vaccines have been designed using hcv structural proteins to control the viral infection. the core nucleocapsid protein is one of the most conserved proteins and a desirable target for hcv vaccines, especially the protein-based vaccines. in cur...

the aim of this experiment was to study the effect of in ovoinjection of royal jelly (rj) on growth performance and immune response in broiler chickens challenged with newcastle disease virus. a total of 200 hatching eggs were divided into four groups of 50 eggs each one using a completely randomized design. the eggs were injected with sterilized sodium bicarbonate buffer (ph=10.4) or rj (88%) ...