background and objectives: macrolide, lincosamide and streptogramin type b (mlsb) antibiotics are important in the treatment of staphylococcus aureus infections and existence of isolates with ability to resist against mlsb antibiotics is worrisome. materials and methods: in this cross sectional study, 101 s. aureus isolates were collected from patients of five selected hospitals in tehran over ...

INTRODUCTION Staphylococcus aureus produces a variety of diseases among children, ranging from skin and soft tissue infections to invasive life-threatening diseases. Since 1990, an increasing number of diseases produced by community-associated methicillin-resistant S. aureus (CA-MRSA) isolates have been reported. The aim of this study was to describe the importance and the microbiological chara...

Methicillin-resistant Staphylococcus aureus (MRSA) has been listed by the World Health Organization as a priority antibiotic-resistant nosocomial pathogen in urgent need of new antimicrobials [1]. Plasmids are key factor pathology and epidemiology MRSA isolates play important roles their evolution. In our on-going efforts to better understand genetic background molecular from Terengganu, Malays...

INTRODUCTION Clindamycin is an alternative antibiotic in the treatment of Staphylococcus aureus (S.aureus) infections, both in infections by methicillin susceptible and resistant (MSSA and MRSA) strains. The major problem of use of clindamycin for staphylococcal infections is the presence of inducible clindamycin resistance that can lead to treatment failure in such infections. AIM To determi...

The widespread use of Macrolide Lincosamide Streptogramin B (MLSB) antibiotics has led to an increase in the resistant strains. Although Clindamycin is effective against MRSA but its use in the presence of Erythromycin can lead to induction of cross-resistance among members of the MLSB group which could limit the effectiveness of this drug. Furthermore, at times, some strains are also harbored ...

background and objectives: staphylococcus aureus is an important cause of nosocomial and community-acquired infections in every region of the world. clindamycin is one of the alternative agents used to treat s. aureus infections and accurate identification of clindamycin resistance is important to prevent therapeutic failure. unfortunately, inducible clindamycin resistance is not detected by st...

Abstract Objectives To phenotypically and genetically characterize the antibiotic resistance determinants associated mobile genetic elements (MGEs) among macrolide-resistant (MR) Streptococcus pyogenes [Group A streptococci (GAS)] clinical isolates collected in Barcelona, Spain. Methods Antibiotic susceptibility testing was performed by microdilution. Isolates were emm MLST typed 55 whole-genom...