Immune-mediated hemolytic anemia (IMHA) is a condition in which autoantibodies bind to endogenous antigens on the erythrocyte membrane, leading to complement or antibody mediated red blood cell destruction. These antigens can be created as part of the normal immune response to an abnormal antigen (i.e. band-3, peroxiredoxin-2, or epitope created by an infectious disease) or due to an abnormal i...

BACKGROUND Immune-mediated hemolytic anemia (IMHA) is the most common hematologic immune-mediated disease in dogs. Complement fixation on erythrocytes causes hemolysis. Complement inhibition decreases hemolysis in people with the hemolytic disease and also may prove effective in treating IMHA in dogs. HYPOTHESIS/OBJECTIVES Evaluate the in vitro efficacy of 2 complement inhibitors used in huma...

Imha Reservoir has both a water transfer tunnel connecting Andong and selective withdrawal facility (SWF), which enable the innovative operation of reservoir. Although these facilities had not been equipped when constructed in 1993, structural measures were applied afterward as needed for effective reservoir operation. The was 2015 to minimize spillway discharge during floods by moving other wi...

BACKGROUND India is revising its mental health legislation with the Indian Mental Healthcare Act 2017 (IMHA). When implemented, this legislation will apply to over 1.25 billion people. In 2005, the World Health Organization (WHO) published a Resource Book (WHO-RB) on mental health, human rights and legislation, including a checklist of 175 specific items to be addressed in mental health legisla...

Immune-mediated hemolytic anemia (IMHA) is a common type of anemia in dogs and cats that results from a type II hypersensitivity reaction.The disease is most common in middle-aged female dogs, especially American cocker spaniels.The common clinical signs are associated with severe anemia and the resultant inflammatory response.There is no pathognomonic test for IMHA, but the following are sugge...

This article will introduce the concept of Knowledge Translation (KT), as defined and used by the Canadian Institutes of Health Research (CIHR). The Institute of Musculoskeletal Health and Arthritis (IMHA), one of the 13 institutes under the umbrella of CIHR, has created the Knowledge Exchange Task Force (KETF) to research KT and to determine how to best develop and implement KT initiatives wit...

Background: Splenic infarction (SI) is a rare clinical entity seldom encountered in veterinary medicine. Its most frequent causes include thromboembolic status, splenomegaly, and cardiac disease. Although thrombotic elements from the circulation provide the most common context for thromboembolic SIs, immune-mediated hemolytic anemia (IMHA) has not been reported as an underlying...

TFA alone was found to be remarkably effective for the intramolecular hydroarylation (IMHA) of alkynes when employed as a solvent in the cyclization of 3-alkynyl substituted 2-(indol-3-yl)quinoxalines. This simple and metal free cyclization method afforded a range of indolophenazines as new and potential cytotoxic agents. The use of excess TFA was found to be crucial for the success of this rea...

Immune-mediated hemolytic anemia (IMHA) is a common cause of anemia in dogs. The immune aggression towards erythrocytes can be triggered by many pathological conditions such as infection, inflammatory disease or neoplasia. Upon ruling out any eliciting conditions, a diagnosis of the primary immune-mediated disease can be made. In this particular case of severe anemia (tested positive for circul...

The International Mental Health Assessment (IMHA) was developed to provide efficient screening facilitate prevention and early intervention among employees or community adults at three levels of analysis: a P-factor general functioning tendency toward disorder; broad spectra internalizing externalizing tendencies for life difficulties; nine subscales common, familiar psychological behavioral he...