Purpose Radiolabeled antibodies and peptides hold promise for molecular radiotherapy but are often limited by a low payload resulting in inadequate delivery of radioactivity to tumour tissue and, therefore, modest therapeutic effect. We developed a facile synthetic method of radiolabeling indium-111 (111In) to epidermal growth factor (EGF)-gold nanoparticles (111In-EGF-Au NP) with a high payloa...

Many biological systems employ allosteric regulatory mechanisms, which offer a powerful means of directly linking a specific binding event to a wide spectrum of molecular functionalities. There is considerable interest in generating synthetic allosteric regulators that can perform useful molecular functions for applications in diagnostics, imaging and targeted therapies, but generating such mol...

During data hiding, distortions are introduced in an original image because of quantization errors, bit-replacement, or truncation at the grayscale limit. These distortions are irreversible and visible which are unacceptable in some applications like medical imaging. However, the reversible watermarking technique overcomes this problem by retrieving the original image from the watermarked image...

For remote sensing missions, the fractionated functionality of CubeSats provides a potential way to reduce cost and risks while maintaining comparable operational capabilities. This paper describes two CubeSat remote sensing missions developed by The Aerospace Corporation. The CubeSat Multispectral Observation System (CUMULOS) and R3 sensors will be hosted on 3U CubeSats developed by Aerospace....

Presently, flight systems designed to perform payload -centric maneuvers require preconstructed procedures and special hand-tuned guidance modes. To enable intelligent maneuvering via strong coupling between the goals of payload-directed flight and the autopilot functions, there exists a need to rethink traditional autopilot design and function. Research into payload directed flight examines se...

ESA’s Proba micro-satellite, launched on October 22, 2001, is in an elliptical 600 km LEO Sun-synchronous orbit. Principally meant for the in-orbit evaluation of new spacecraft technologies and satellite operational autonomy, Proba is also being employed as a flight opportunity for a range of Space Environment and Earth Observation instruments, to take advantage of the pointing and agility capa...

Drug delivery to the gastrointestinal (GI) tract is highly challenging due to the harsh environments any drug- delivery vehicle must experience before it releases it's drug payload. Effective targeted drug delivery systems often rely on external stimuli to effect release, therefore knowing the exact location of the capsule and when to apply an external stimulus is paramount. We present a drug d...

The Schwarzschild solution is used to find the exact relativistic motion of a payload in the gravitational field of a mass moving with constant velocity. At radial approach or recession speeds faster than 1/ 2 3 times the speed of light, even a small mass gravitationally repels a payload. At relativistic speeds, a suitable mass can quickly propel a heavy payload from rest nearly to the speed of...

Abstract Kplo-MAGnetometer (KMAG) is one of the scientific instruments Korea Pathfinder Lunar Orbiter (KPLO) set to be launched in 2022. Its objectives are magnetic field investigation and technical demonstration near surface Moon. Specifically, it will investigate lithospheric magnetism Moon measure electromagnetic wave properties lunar surface. It consists three fluxgate magnetometers on a 1....