نتایج جستجو برای: il33 protein
تعداد نتایج: 1234746 فیلتر نتایج به سال:
334 TRPV3 modulates mast cells biological activity via stimulating IL33 release in atopic dermatitis
Transient receptor potential vanilloid 3 subtype (TRPV3) plays an important role in pruritus. From our previous work, chronic pruritus dominantly attenuated TRPV3 knockout mice (TRPV3 KO). We found functional coupled with protease-activated 2 (PAR2) keratinocytes inducing TSLP releasing atopic dermatitis (AD). With bioinformatics investigation, we that mast cells of KO infiltrated less the derm...
search Institute, Cleveland, OH; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA; Department of Pediatrics, University of Virginia Health Systems, Charlottesville, VA; Brigham & Women’s Hospital, Harvard University, Boston, MA; Departments of Medicine and Public Health Sciences, University of Wisconsin Hospitals and Clinics, Madison, WI; Medicine, University of Pittsb...
BACKGROUND Asthma is a heterogeneous disease in which age of onset plays an important role. OBJECTIVE We sought to identify the genetic variants associated with time to asthma onset (TAO). METHODS We conducted a large-scale meta-analysis of 9 genome-wide association studies of TAO (total of 5462 asthmatic patients with a broad range of age of asthma onset and 8424 control subjects of Europe...
search Institute, Cleveland, OH; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA; Department of Pediatrics, University of Virginia Health Systems, Charlottesville, VA; Brigham & Women’s Hospital, Harvard University, Boston, MA; Departments of Medicine and Public Health Sciences, University of Wisconsin Hospitals and Clinics, Madison, WI; Medicine, University of Pittsb...
Reasons for the development of chronic tendon pathologies are still under debate and more basic knowledge is needed about the different diseases. The aim of the present study was therefore to characterize different acute and chronic Achilles tendon disorders. Achilles tendon samples from patients with chronic tendinopathy (n = 7), chronic ruptures (n = 6), acute ruptures (n = 13), and intact te...
Background Optimizing methods for the study of allergic rhinitis (AR), especially when using samples likely containing small amounts of material for analysis, ensures the integrity of results that may potentially enhance the understanding of AR disease mechanisms. In order to conduct future mRNA expression analysis, examining the differential expression of AR mediators such as IL33, TSLPR, HPGD...
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