نتایج جستجو برای: igg response

تعداد نتایج: 1005651  

Journal: :The Journal of Experimental Medicine 2000
Michael R. Ehrenstein H. Terence Cook Michael S. Neuberger

Serum immunoglobulin (Ig)M provides the initial response to foreign antigen and plays a regulatory role in subsequent immune response development, accelerating the production of high-affinity IgG. Here we show that mice deficient in serum IgM have an increased propensity to spontaneous autoimmunity as judged by the development with age of serum IgG anti-DNA antibodies and the renal deposition o...

Journal: :Journal of immunology 2012
Swadhinya Arjunaraja Paola Massari Lee M Wetzler Andrew Lees Jesus Colino Clifford M Snapper

In vivo anti-polysaccharide Ig responses to isolated polysaccharide (PS) are T cell independent, rapid, and fail to generate memory. However, little is known regarding PS-specific Ig responses to intact gram-positive and gram-negative extracellular bacteria. We previously demonstrated that intact heat-killed Streptococcus pneumoniae, a gram-positive bacterium, elicited a rapid primary pneumococ...

Adama Tali Alioune Dieye, Babacar Mbengue Bacary Diatta Birahim Niang Olivier Garraud Ronald Perraut

Background: Cerebral malaria (CM) is one of the major causes of death in African populations infected with Plasmodium falciparum. Only 1% of infected subjects develop CM. The reasons for these differences are not fully understood, but it is likely that the host humoral response against blood-stage antigens plays a role in protection from malaria, although the precise targets and mechanisms medi...

Journal: :Multiple sclerosis and related disorders 2021

BackgroundNeuromyelitis optica spectrum disorders (NMOSDs) are a group of chronic immune-mediated demyelinating diseases the central nervous system. Their pathophysiology dependent on humoral mediated responses caused by autoreactive IgG antibodies against aquaporin-4 water channels (AQP4-IgG) or myelin oligodendrocyte glycoprotein (MOG-IgG). Plasma exchange (PLEX) has proved to be beneficial t...

Journal: :European journal of neurology 2003
V Lejon C J M Sindic M-P Van Antwerpen F Doua N Djé P Solano V Jamonneau I Wouters P Büscher

Quantitative and qualitative techniques for assessment of the intrathecal humoral immune response in human African trypanosomiasis were compared, and their diagnostic potential for detection of the meningo-encephalitic stage of the disease was evaluated. Total and trypanosome specific immunoglobulin G (IgG) and IgM intrathecal synthesis were studied in paired cerebrospinal fluid (CSF) and blood...

Journal: :iranian journal of allergy, asthma and immunology 0
a. amirzargar s. feghhi m.h. nicknam n. saki

otitis media with effusion (ome) is very common in pediatric patients. immune reactions in serum and middle ear system play roles in the etiology, pathogenesis and prevention of otitis media. immunologically active antigens interact with immunocompetent cells in the lamina propria of the middle ear to produce a local immune response. in this investigation, 32 sera and 50 middle ear fluid sample...

The effects of the human and bovine LSF (derived from sera) as well as their purified fractions were studied on murine lymphocytes reactions indicated by blast transformation (BT) assay, mixed lymphocyte culture (MLC) and IgG synthesis. The results indicated that bovine lipid suppressor factor (LSF) has significant immunosuppressive activity on lymphocytes proliferation both in BT and MLC ...

2017
Joakim J. E. Bergström Hui Xu Birgitta Heyman

Specific IgG, passively administered together with particulate antigen, can completely prevent induction of antibody responses to this antigen. The ability of IgG to suppress antibody responses to sheep red blood cells (SRBCs) is intact in mice lacking FcγRs, complement factor 1q, C3, or complement receptors 1 and 2, suggesting that Fc-dependent effector functions are not involved. Two of the m...

Journal: :Japanese Journal of Applied Physics 2021

Abstract We present a wireless quartz crystal microbalance (QCM) biosensor fabricated using MEMS technology. The QCM contains 125 MHz AT-cut resonator embedded in the microchannel. Because of compact design, is suitable for mass production and device miniaturization. performed immunoglobulin G (IgG) detection measurements with different concentrations IgG. limit was 1 ng ml –1 or less, which su...

Journal: :Infection and immunity 1977
K O Kalimo R J Marttila K Granfors M K Viljanen

A solid-phase radioimmunoassay developed in our laboratory for detection of human viral immunoglobulin M (IgM) and IgG antibodies was applied to demonstrate human class-specific antibody response against capsid, envelope, and excreted antigens of herpes simplex virus type 1. In primary infections, a clear IgM and IgG antibody response was found predominantly against the envelope components, whe...

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