[email protected] INTRODUCTION: The observation that an experimental pinealectomy in newborn chickens leads to a spinal deformity similar to idiopathic scoliosis in humans initiated a new neuroendocrine hypothesis for the cause of idiopathic scoliosis. A deficiency of melatonin, which is the principal product of the pineal gland, was believed to be responsible for this deformity, because b...

BACKGROUND Scoliosis is a feature of several genetic disorders that are also associated with aortic aneurysm, including Marfan syndrome, Loeys-Dietz syndrome, and type-IV Ehlers-Danlos syndrome. Life-threatening complications of aortic aneurysm can be decreased through early diagnosis. Genetic screening for mutations in populations at risk, such as patients with adolescent idiopathic scoliosis,...

Improper postural alignment and trunk stability caused by idiopathic scoliosis may affect postural balance pattern during sitting. In this study, we conducted pressure data analysis for evaluation of postural balance in patients with idiopathic scoliosis by using pressure sensor system. Subjects were divided into three groups: a control group, scoliosis with left convex side of the curve group,...

Scoliosis is a complex three-dimensional deformity that is usually considered in the frontal plane without references to curvature in other planes. An important feature of idiopathic scoliosis deformity is the horizontal plane rotation (vertebral axial rotation). This rotation is thought to be significant for initiation and progression of idiopathic scoliosis (Adams W, 1865). Somerville's (1952...

The scoliosis observed in chickens after pinealectomy resembles that seen in humans with an adolescent idiopathic scoliosis, suggesting that melatonin deficiency may be responsible. However, to date there have been no studies of pineal gland glucose metabolism in patients with adolescent idiopathic scoliosis that might support this hypothesis. We examined the excretion of urinary 6-sulfatoxyl-m...

Background According to SRS (Scoliosis research Society) Juvenile idiopathic scoliosis (JIS) is defined as a scoliosis that is first diagnosed between the age of 4 and 10 years. The natural history is characterized by an early deformity that leads to a major but extremely variable progression risk throughout growth. Objectives of the study is verifying the efficacy of a complete conservative tr...

Idiopathic scoliosis is a three-dimensional deformity of the spine with lateral curvature combined with vertebral rotation. The primary lesion, however, lies in the median sagittal plane, taking the form of a lordosis. It was first described by Hippocrates, and the term “scoliosis” was first used by Galen (AD 131–201). Although the clinical manifestations of scoliosis have been well described, ...

BACKGROUND The etiology of idiopathic scoliosis remains unknown and different factors have been suggested as causal. Hereditary factors can also determine the etiology of the disease; however, the pattern of inheritance remains unknown. Autosomal dominant, X-linked and multifactorial patterns of inheritances have been reported. Other studies have suggested possible chromosome regions related to...

abstract   background: to evaluate proximal junctional segment changes in adolescent idiopathic scoliosis(ais) the posterior spinal fusion and also instrumentation also and finding of probable risk factors, were all considered in this study.   methods: we retrospectively reviewed radiographs of 121 consecutive patients who underwent posterior spinal fusion for ais from t3 or below, with a mean ...