PURPOSE This study aimed to analyze the clinical patterns and etiology of uveitis in Isfahan, Iran. METHODS In this descriptive research, the records of 2016 patients with uveitis referred to a tertiary eye care centers were examined. Age, sex, clinical and anatomical features, and etiology of disease were recorded and analyzed. RESULTS The mean age of onset of uveitis was 33.76 years and t...

Vogt-Koyanagi-Harada (VKH) disease, also known as uveomeningitic syndrome, is an idiopathic multisystem inflammatory disease with bilateral uveitis. Patients with bilateral anterior uveitis with vitiligo, poliosis, alopecia, and dysacousia were first described by Vogt in 1906 and then Koyanagi in 1929. Harada described a case of posterior uveitis with exudative retinal detachment and pleocytosi...

Anterior uveitis (AU), inflammation of the iris, choroid or ciliary body, can cause significant eye morbidity, including visual loss. In the pediatric age group, the most common underlying diagnosis for AU is juvenile idiopathic associated uveitis and idiopathic AU, which are the focus of this paper. AU is often resistant to medications such as topical corticosteroids and methotrexate. In the p...

OBJECTIVES To evaluate the association of adalimumab trough levels and anti-adalimumab antibodies with activity of uveitis in juvenile idiopathic arthritis-related uveitis. METHODS This was a retrospective observational case series in a clinical setting at the Department of Ophthalmology, Helsinki University Hospital, Finland in 2014-2016. Thirty-one paediatric patients with chronic anterior ...

purpose: to evaluate the role of active uveitis on refractive errors changes. methods: a cohort single group study was conducted on patients with acute or recurrent uveitis. cyclorefraction was performed in both phases of active and quiescent. sphere, cylinder and sphere equivalent power were compared in active and quiescent phases and analyzed statistically. results: sixty-six patients (eighty...

Purpose HLA class I-specific killer cell immunoglobulin-like receptors (KIR) gene and HLA gene combinations have been associated with autoimmune uveitis (e.g., birdshot chorioretinopathy (BCR) and Vogt-Koyanagi-Harada syndrome (VKH)). In oligoarticular juvenile idiopathic arthritis (JIA), uveitis is one of the most serious complications, affecting approximately 20% of patients. Multiple studies...

AIMS To determine whether HLA-B27 typing helps the clinician in the diagnostic examination of uveitis in a HLA-B27 rich population and also whether the clinical picture of HLA-B27 positive unilateral acute or recurrent anterior uveitis (AAU) is distinguishable from the idiopathic negative form. METHODS During a 3 year period 220 consecutive patients with undetermined uveitis at onset were exa...

Abstract Background The early detection of uveitis associated with systemic inflammatory disease in children is important for proper treatment and prognosis. However, the diagnosis may be delayed because difficulties childhood examinations minor symptoms. objective our study was to identify pattern investigate frequency clinical features rheumatic diseases pediatric patients uveitis. Methods Th...

PURPOSE To compare cell types and cytokines in aqueous humor from patients with uveitis either occurring in association with a systemic disease or apparently isolated and not associated with a systemic disease. METHODS Cells were collected by centrifugation of fresh aqueous humor from uveitis and controls, and immunofluorescence techniques were performed with markers for T cells, B cells, and...