The late afterhyperpolarizing potential (AHP) that follows the action potential in intrinsic primary afferent neurons of the gastrointestinal tract has a profound influence on their firing patterns. There has been uncertainty about the identity of the channels that carry the late AHP current, especially in guinea pigs, where the majority of the physiological studies have been made. In the prese...

We examined the membrane potentials and firing properties of motor cortical neurons recorded intracellularly in awake, behaving primates. Three classes of neuron were distinguished by 1) the width of their spikes, 2) the shape of the afterhyperpolarization (AHP), and 3) the distribution of interspike intervals. Type I neurons had wide spikes, exhibited scoop-shaped AHPs, and fired irregularly. ...

Effective supply chain design calls for robust analytical models and design tools. Previous works in this area are mostly Operation Research oriented without considering manufacturing aspects. Recently, researchers have begun to realize that the decision and integration effort in supply chain design should be driven by the manufactured product, specifically, product characteristics and product ...

Small conductance Ca(2+)-activated K(+) channels (SK) regulate action potential (AP) firing properties and excitability in many central neurons. However, the functional roles of SK channels of parasympathetic cardiac motoneurons (PCMNs) in the nucleus ambiguus have not yet been well characterized. In this study, the tracer X-rhodamine-5 (and 6)-isothiocyanate (XRITC) was injected into the peric...

The purpose of this paper is to extend the theory of Hierarchies Consistency Analysis (HCA) to establish a multiple structures evaluation model for the AHP. Traditionally, the AHP process is based on a single evaluation hierarchy, according to statistics and group decision theories, a more objective evaluation will be obtained if we can compromise several estimates. We will construct several di...