To the Editor, Multiple risk factors for osteoporotic fracture, inclu ding osteoporosis and falls, are widely known. It is also clear that osteoporotic fractures impose a significant morbidity and mortality in the elderly, with major mone tary costs associated. Recent studies suggest that chronic hyponatremia (serum [Na+] < 135mEq/L), albeit slight (serum [Na+] = 125-134 mEq/L), may be associat...

Rhabdomyolysis is characterized by the destruction of skeletal muscle tissue, and its main causes are trauma, toxic substances and electrolyte disturbances. Among the latter is hyponatremia-induced rhabdomyolysis, a rare condition that occurs mainly in patients with psychogenic polydipsia. Psycogenic polydipsia mostly affects patients with schizophrenia, coursing with hyponatremia in almost 25%...

BACKGROUND AND PURPOSE Hyponatremia is the most frequent electrolyte disturbance in critical care. Across various disciplines, hyponatremia is associated with increased mortality and longer hospital stay, yet in intracerebral hemorrhage (ICH) no data are available. This the first study that investigated the prevalence and clinical associations of hyponatremia in patients with ICH. METHODS Thi...

Death following tonsillectomy in children is very rare. It is most commonly due to bleeding or aspiration. But, there is another potentially lethal complication following the pediatric tonsillectomy, post-surgical hyponatremia. Acute hyponatremia can lead to catastrophic neurological sequelae. Although this cmplication is not related to the surgical technique, it is potentially life-threatening...

INTRODUCTION Hyponatremia (serum sodium<135 mMol/L) is the commonest electrolyte imbalance encountered in clinical practice. It is associated with multiple poor clinical outcomes including increased mortality, longer hospital stay, falls and fractures. Prevalence is higher in frail patient groups, and elderly patients with fragility fractures (EPFF) are particularly susceptible. Euvolemic hypon...

PURPOSE Hyponatremia is one of the most common adverse effects in patients treated with oxcarbazepine (OXC). Most patients with OXC-induced hyponatremia are asymptomatic, so the presence of severe or symptomatic hyponatremia, which requires electrolyte correction or discontinuation of OXC therapy, has more important clinically implications. However, data for OXC-induced severe and symptomatic h...

Decreased serum sodium concentration is a rather frequent electrolyte disorder in the elderly population because of the presence of factors contributing to increased antidiuretic hormone, the frequent prescription of drugs associated with hyponatremia and also because of other mechanisms such as the "tea and toast" syndrome. The aim of this review is to present certain challenges in the evaluat...

Hyponatremia has been reported in the elderly with hypothyroidism and myxedema, but this has not been a universal finding in clinical studies and there have been only a few reports in children. We report a case of an infant who developed hyponatremia due to severe primary hypothyroidism. A 4-month-old ex-preterm male, who had been euthyroid on the newborn screen, developed unexplained hospital-...

Dysregulation of the neuroendocrine system is a frequent complication after traumatic brain injury (TBI). Symptoms of these hormonal abnormalities might be subtle and thus easily ignored. Hyponatremia usually indicates underlying disorders that disrupt fluid homeostasis. In most patients with TBI, hyponatremia is a feature of the syndrome of inappropriate antidiuretic hormone (SIADH) secretion ...

Hyponatremia is one of the most frequent laboratory findings in hospitalized children. We present an unusual case of recurrent hyponatremia in a 16-year-old female secondary to acute intermittent porphyria (AIP), a rare inborn error of metabolism. The proposed mechanism of the hyponatremia and recommended treatment are discussed. Although rare, AIP should be considered in children with recurren...