Thyroid disease has profound effects on cardiovascular function. Hypo- and hyperthyroidism, for example, are associated with reduced and increased maximal endothelium-dependent vasodilation respectively. We therefore hypothesized that the capacity for vascular nitric oxide (NO) formation is decreased in hypothyroidism and increased in hyperthyroidism. To test this hypothesis, rats were made hyp...

Hyponatremia and hypernatremia are complex clinical problems that occur frequently in full term newborns and in preterm infants admitted to the Neonatal Intensive Care Unit (NICU) although their real frequency and etiology are incompletely known. Pathogenetic mechanisms and clinical timing of hypo-hypernatremia are well known in adult people whereas in the newborn is less clear how and when hyp...

Antecedent hypoglycemia leads to impaired counterregulation and hypoglycemic unawareness. To ascertain whether antecedent portal vein hypoglycemia impairs portal vein glucose sensing, thereby inducing counterregulatory failure, we compared the effects of antecedent hypoglycemia, with and without normalization of portal vein glycemia, upon the counterregulatory response to subsequent hypoglycemi...

The effect of thyroid status on arterial baroreflex function and autonomic contributions to resting blood pressure and heart rate (HR) were evaluated in conscious rats. Rats were rendered hyperthyroid (Hyper) or hypothyroid (Hypo) with triiodothyronine and propylthiouracil treatments, respectively. Euthyroid (Eut), Hyper, and Hypo rats were chronically instrumented to measure mean arterial pres...

In previous work we presented argumentation schemes to capture the CATO and value based theory construction approaches to reasoning with legal cases with factors. We formalised the schemes with ASPIC+, a formal representation of instantiated argumentation. In ASPIC+ the premises of a scheme may either be a factor provided in a knowledge base or established using a further argumentation scheme. ...

Abstract. This paper obtains all solvable 3-Lie algebras with the m-dimensional filiform 3-Lie algebra N (m ≥ 5) as a maximal hypo-nilpotent ideal, and proves that the m-dimensional filiform 3-Lie algebra N can’t be as the nilradical of solvable non-nilpotent 3-Lie algebras. By means of one dimensional extension of Lie algebras to the 3-Lie algebras, we get some classes of solvable Lie algebras...