This study investigated the use of the TruView xylenol-orange-based gel and VISTA optical CT scanner (both by Modus Medical Inc, London, Canada), for use in verifying the accuracy of planned dose distributions for hypo-fractionated (stereotactic) vertebral treatments. Gel measurements were carried out using three stereotactic vertebral treatments and compared with planned doses calculated using...

There is a clear dose response for localized prostate cancer radiotherapy and there probably is a radiobiological rationale for hypo-fractionation. Combining the two should maximize tumor control and increase the therapeutic ratio. This study examines the rationale and technical feasibility of CyberKnife radiotherapy (a robotic arm-driven linear accelerator) for localized prostate cancer. Its a...

Patients with early stage high-risk prostate cancer (prostate specific antigen > 20, Gleason score > 7) are at high risk of recurrence following prostate cancer irradiation. Radiation dose escalation to the prostate may improve biochemical-free survival for these patients. However, high rectal and bladder dose with conventional three-dimensional conformal radiotherapy may lead to excessive gast...