From July 1998 to November 1999 we have followed up 15712 deliveries (12044 vaginal and 3668 cesarean section) in our hospital. Among these, 182 cases were primarily diagnosed as intrauterine growth restriction (IUGR) and 248 pregnancies were complicated with hypertensive disorders. In these two groups we have investigated the outcome of the neonates. Neonatal weight under the 10th percent...

Placenta is a vital organ for maintaining pregnancy and promoting normal foetal development. Foetal outcome is adversely influenced by pathological changes observed in placenta. Pregnancy complications like hypertension are reflected in placenta. The objective was to assess the morphology of placenta in normotensive and hypertensive pregnancies and to correlate the morphometric analysis with fe...

Background: Hypertensive disorders complicate 5%–10% of all pregnancies and contribute greatly to maternal morbidity and mortality rates. Dangerous hypertension can cause cerebrovascular hemorrhage, hypertensive encephalopathy, and can trigger eclamptic convulsions. Blood pressure (BP) ≥160/110 mmHg in pregnancy requires prompt treatment. Both nifedipine and intravenous (IV) labetalol are effec...

The authors aimed to compare renal function by estimated glomerular filtration rate and albuminuria in 3 groups of women: nulliparous women, women with a history of normotensive pregnancies, and women with a history of at least one hypertensive pregnancy. Women who participated in the second Family Blood Pressure Program Study visit (2000-2004) and had serum creatinine and urine albumin measure...

Adverse infant outcomes often rise in the aftermath of disaster, but few studies have assessed the effects of disaster on maternal health. 1091 southern Louisiana women were interviewed about their pregnancy history, including pregnancy complications. Associations between oil spill exposures and gestational diabetes, hypertensive disorders, and nausea/vomiting were assessed for all reported pre...

OBJECTIVE To examine differences in late fetal death rates in association with determinants of small for gestational age fetuses. DESIGN Population based cohort study. SUBJECTS 1 026 249 pregnancies without congenital malformations. SETTING Sweden 1983-92. MAIN OUTCOME MEASURE Late fetal death rate. RESULTS Depending on underlying determinants late fetal death rates were greatly incre...

Deficient NO formation has been implicated in hypertensive disorders of pregnancy. However, no previous study has compared the circulating nitrite concentrations in healthy pregnant women with those found in hypertensive disorders of pregnancy. Moreover, 2 antiangiogenic factors produced in the placenta (soluble fms-like tyrosine kinase-1 and soluble endogline) may affect NO formation during pr...