BACKGROUND Preeclampsia and gestational hypertensive disorders are thought to occur due to endothelial cell dysfunction and abnormal placentation, triggered by angiogenesis-related factors yet undetermined. The aim of this study was to investigate whether a genetic polymorphism (SNP) of Histidine-rich glycoprotein (HRG), HRG C633T SNP, is associated with gestational hypertensive disorders. ME...

Hypertensive disorders (HDs) as the most prevalent medical problem during pregnancy, predispose the patient to a lot of comorbidities and may even cause maternal or fetal death. The rate of infertility has been increasing in recent decades. So, we collected and summarized data about the co-existence of these two entities and found that HDs are somewhat more common in women receiving fertility t...

Pregnancy-induced hypertensive disorders can lead to maternal and perinatal morbidity and mortality, but the cause of these conditions is not well understood. We have systematically reviewed and performed a meta-analysis of epidemiological studies investigating the association between exposure to ambient air pollution and pregnancy-induced hypertensive disorders including gestational hypertensi...

BACKGROUND Hypertensive disorders of pregnancy are a major cause of morbidity and mortality. The objective was to estimate the disease burden attributable to hypertensive disorders of pregnancy in two referral hospitals in Uganda. METHODS Through a prospective cohort study conducted in Jinja and Mulago hospitals in Uganda from March 1, 2013 and February 28, 2014, hypertension-related cases we...

OBJECTIVE The present study aimed at assessing the association between environmental temperature and the relative humidity of the air with frequency of hypertensive disorders of pregnancy. METHODS A prospective and retrospective, descriptive, ecological study was held at a teaching maternity in Recife, Brazil. Data from all 26.125 pregnant women admitted between 2000 and 2006 were analysed an...

Aim: This study aimed to investigate the effects of relaxin (RLX) on hypertensive disorders pregnancy (HDP) and fetal growth restriction (FGR) using a nitric oxide synthase (NOS) inhibitor-induced HDP murine model.

Hypertensive disease is one of the urgent problems in modern cardiology. It known that a huge variety comorbid states influence development hypertensive disease, i. e. neurogenic hyperventilating syndrome. sign and marker suprasegmental vegetative structures disorders destabilize homeostasis, initiate specific pathological processes, which are base somatization disorders, including heart disord...

Hypertension is a common complication of pregnancy and remains a major cause of maternal and perinatal morbidity and mortality worldwide. Hypertensive disorders vary from mild gestational hypertension to severe pre-eclampsia, which remains one of the leading causes of maternal death in the UK. Although there have been major advances in understanding the pathophysiology of the disease in recent ...

The purpose of this prospective study was to determine the effect of calcium supplementation in the incidence of hypertensive disorders of pregnancy (gestational hypertension and pre-eclampsia) in nulliparous and high risk women. 300 pregnant women in the 24th week of gestation at the beginning of the study were entered into a double-blind randomized trial. 143 of them who had a positive ro...