Hypersplenism in chronic liver diseases (CLD) is characterized by splenomegaly and thrombocytopenia. Thrombocytopenia is a contraindication to percutaneous liver biopsy, which is an important procedure for diagnostic work-up of liver disease. In children, the etiologies of CLD are more diverse than in adults, and include congenital, metabolic and infiltrative diseases as well as viral hepatitis...

BACKGROUND This study systematically compared the efficacy and safety of simultaneous hepatectomy and splenectomy (HS) with hepatectomy (H) alone in patients with hepatocellular carcinoma (HCC) and hypersplenism. METHODS The PubMed, Web of Science, Science Direct, EMBASE, and Cochrane Library databases were systematically searched by two independent researchers through to March 31, 2015 to id...

Myelofibrosis (MF) is a rare disorder that classified as one of the myeloproliferative disorders. It BCR-ABL1- negative neoplasm characterized by abnormal proliferation hemopoietic stem cells within bone marrow, which leads to overproduction fibrous tissue. Our patient young girl 17 year old presented with lump in left upper abdomen, shortness breath & generalized swelling. The diagnosis wa...

Objective: To determine the frequency of different causes of pancytopenia on bone marrow examination. Study Design: Descriptive study. Place and Duration of Study: The study was carried out at Haematology (pathology) department of Army Medical College, National University of Sciences and Technology (NUST) and Military Hospital Rawalpindi from Jan 2012 – Dec 2012. Patients and Methods: Total 67 ...